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A Four-Gene Promoter Methylation Marker Panel Consisting of GREM1, NEURL, LAD1, and NEFH Predicts Survival of Clear Cell Renal Cell Cancer Patients.
van Vlodrop IJH, Joosten SC, De Meyer T, Smits KM, Van Neste L, Melotte V, Baldewijns MMLL, Schouten LJ, van den Brandt PA, Jeschke J, Yi JM, Schuebel KE, Ahuja N, Herman JG, Aarts MJ, Bosman FT, Van Criekinge W, van Engeland M. van Vlodrop IJH, et al. Among authors: melotte v. Clin Cancer Res. 2017 Apr 15;23(8):2006-2018. doi: 10.1158/1078-0432.CCR-16-1236. Epub 2016 Oct 18. Clin Cancer Res. 2017. PMID: 27756787
NDRG4, an early detection marker for colorectal cancer, is specifically expressed in enteric neurons.
Vaes N, Lentjes MHFM, Gijbels MJ, Rademakers G, Daenen KL, Boesmans W, Wouters KAD, Geuzens A, Qu X, Steinbusch HPJ, Rutten BPF, Baldwin SH, Sharkey KA, Hofstra RMW, van Engeland M, Vanden Berghe P, Melotte V. Vaes N, et al. Among authors: melotte v. Neurogastroenterol Motil. 2017 Sep;29(9). doi: 10.1111/nmo.13095. Epub 2017 May 19. Neurogastroenterol Motil. 2017. PMID: 28524415
The enteric nervous system in gastrointestinal disease etiology.
Holland AM, Bon-Frauches AC, Keszthelyi D, Melotte V, Boesmans W. Holland AM, et al. Among authors: melotte v. Cell Mol Life Sci. 2021 May;78(10):4713-4733. doi: 10.1007/s00018-021-03812-y. Epub 2021 Mar 26. Cell Mol Life Sci. 2021. PMID: 33770200 Free PMC article. Review.
Loss of enteric neuronal Ndrg4 promotes colorectal cancer via increased release of Nid1 and Fbln2.
Vaes N, Schonkeren SL, Rademakers G, Holland AM, Koch A, Gijbels MJ, Keulers TG, de Wit M, Moonen L, Van der Meer JRM, van den Boezem E, Wolfs TGAM, Threadgill DW, Demmers J, Fijneman RJA, Jimenez CR, Vanden Berghe P, Smits KM, Rouschop KMA, Boesmans W, Hofstra RMW, Melotte V. Vaes N, et al. Among authors: melotte v. EMBO Rep. 2021 Jun 4;22(6):e51913. doi: 10.15252/embr.202051913. Epub 2021 Apr 23. EMBO Rep. 2021. PMID: 33890711 Free PMC article.
Intestinal multicellular organoids to study colorectal cancer.
Idris M, Alves MM, Hofstra RMW, Mahe MM, Melotte V. Idris M, et al. Among authors: melotte v. Biochim Biophys Acta Rev Cancer. 2021 Dec;1876(2):188586. doi: 10.1016/j.bbcan.2021.188586. Epub 2021 Jun 30. Biochim Biophys Acta Rev Cancer. 2021. PMID: 34216725 Free article. Review.
The gut brain in a dish: Murine primary enteric nervous system cell cultures.
Schonkeren SL, Küthe TT, Idris M, Bon-Frauches AC, Boesmans W, Melotte V. Schonkeren SL, et al. Among authors: melotte v. Neurogastroenterol Motil. 2022 Feb;34(2):e14215. doi: 10.1111/nmo.14215. Epub 2021 Jul 8. Neurogastroenterol Motil. 2022. PMID: 34236124 Free PMC article. Review.
TFAP2B Haploinsufficiency Impacts Gastrointestinal Function and Leads to Pediatric Intestinal Pseudo-obstruction.
Zada A, Kuil LE, de Graaf BM, Kakiailatu N, Windster JD, Brooks AS, van Slegtenhorst M, de Koning B, Wijnen RMH, Melotte V, Hofstra RMW, Brosens E, Alves MM. Zada A, et al. Among authors: melotte v. Front Cell Dev Biol. 2022 Jul 8;10:901824. doi: 10.3389/fcell.2022.901824. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 35874825 Free PMC article.
58 results