Selfors LM - Search Results

1

Simultaneous isolation of hormone receptor-positive breast cancer organoids and fibroblasts reveals stroma-mediated resistance mechanisms.

Hogstrom JM, Cruz KA, Selfors LM, Ward MN, Mehta TS, Kanarek N, Philips J, Dialani V, Wulf G, Collins LC, Patel JM, Muranen T. Hogstrom JM, et al. Among authors: selfors lm. J Biol Chem. 2023 Aug;299(8):105021. doi: 10.1016/j.jbc.2023.105021. Epub 2023 Jul 7. J Biol Chem. 2023. PMID: 37423299 Free PMC article.

2

Lineage-specific silencing of PSAT1 induces serine auxotrophy and sensitivity to dietary serine starvation in luminal breast tumors.

Choi BH, Rawat V, Högström J, Burns PA, Conger KO, Ozgurses ME, Patel JM, Mehta TS, Warren A, Selfors LM, Muranen T, Coloff JL. Choi BH, et al. Among authors: selfors lm. Cell Rep. 2022 Jan 18;38(3):110278. doi: 10.1016/j.celrep.2021.110278. Cell Rep. 2022. PMID: 35045283 Free PMC article.

3

Inhibition of PI3K/mTOR leads to adaptive resistance in matrix-attached cancer cells.

Muranen T, Selfors LM, Worster DT, Iwanicki MP, Song L, Morales FC, Gao S, Mills GB, Brugge JS. Muranen T, et al. Among authors: selfors lm. Cancer Cell. 2012 Feb 14;21(2):227-39. doi: 10.1016/j.ccr.2011.12.024. Cancer Cell. 2012. PMID: 22340595 Free PMC article.

4

Establishment of Patient-Derived Tumor Xenograft Models of Epithelial Ovarian Cancer for Preclinical Evaluation of Novel Therapeutics.

Liu JF, Palakurthi S, Zeng Q, Zhou S, Ivanova E, Huang W, Zervantonakis IK, Selfors LM, Shen Y, Pritchard CC, Zheng M, Adleff V, Papp E, Piao H, Novak M, Fotheringham S, Wulf GM, English J, Kirschmeier PT, Velculescu VE, Paweletz C, Mills GB, Livingston DM, Brugge JS, Matulonis UA, Drapkin R. Liu JF, et al. Among authors: selfors lm. Clin Cancer Res. 2017 Mar 1;23(5):1263-1273. doi: 10.1158/1078-0432.CCR-16-1237. Epub 2016 Aug 29. Clin Cancer Res. 2017. PMID: 27573169 Free PMC article.

5

ERK and p38 MAPK Activities Determine Sensitivity to PI3K/mTOR Inhibition via Regulation of MYC and YAP.

Muranen T, Selfors LM, Hwang J, Gallegos LL, Coloff JL, Thoreen CC, Kang SA, Sabatini DM, Mills GB, Brugge JS. Muranen T, et al. Among authors: selfors lm. Cancer Res. 2016 Dec 15;76(24):7168-7180. doi: 10.1158/0008-5472.CAN-16-0155. Epub 2016 Oct 20. Cancer Res. 2016. PMID: 27913436 Free PMC article.

6

PDEF promotes luminal differentiation and acts as a survival factor for ER-positive breast cancer cells.

Buchwalter G, Hickey MM, Cromer A, Selfors LM, Gunawardane RN, Frishman J, Jeselsohn R, Lim E, Chi D, Fu X, Schiff R, Brown M, Brugge JS. Buchwalter G, et al. Among authors: selfors lm. Cancer Cell. 2013 Jun 10;23(6):753-67. doi: 10.1016/j.ccr.2013.04.026. Cancer Cell. 2013. PMID: 23764000 Free PMC article.

7

Aging-Associated Alterations in Mammary Epithelia and Stroma Revealed by Single-Cell RNA Sequencing.

Li CM, Shapiro H, Tsiobikas C, Selfors LM, Chen H, Rosenbluth J, Moore K, Gupta KP, Gray GK, Oren Y, Steinbaugh MJ, Guerriero JL, Pinello L, Regev A, Brugge JS. Li CM, et al. Among authors: selfors lm. Cell Rep. 2020 Dec 29;33(13):108566. doi: 10.1016/j.celrep.2020.108566. Cell Rep. 2020. PMID: 33378681 Free PMC article.

8

Organoid cultures from normal and cancer-prone human breast tissues preserve complex epithelial lineages.

Rosenbluth JM, Schackmann RCJ, Gray GK, Selfors LM, Li CM, Boedicker M, Kuiken HJ, Richardson A, Brock J, Garber J, Dillon D, Sachs N, Clevers H, Brugge JS. Rosenbluth JM, et al. Among authors: selfors lm. Nat Commun. 2020 Apr 6;11(1):1711. doi: 10.1038/s41467-020-15548-7. Nat Commun. 2020. PMID: 32249764 Free PMC article.

9

Fibroblast-tumor cell signaling limits HER2 kinase therapy response via activation of MTOR and antiapoptotic pathways.

Zervantonakis IK, Poskus MD, Scott AL, Selfors LM, Lin JR, Dillon DA, Pathania S, Sorger PK, Mills GB, Brugge JS. Zervantonakis IK, et al. Among authors: selfors lm. Proc Natl Acad Sci U S A. 2020 Jul 14;117(28):16500-16508. doi: 10.1073/pnas.2000648117. Epub 2020 Jun 29. Proc Natl Acad Sci U S A. 2020. PMID: 32601199 Free PMC article.

10

Differential remodeling of actin cytoskeleton architecture by profilin isoforms leads to distinct effects on cell migration and invasion.

Mouneimne G, Hansen SD, Selfors LM, Petrak L, Hickey MM, Gallegos LL, Simpson KJ, Lim J, Gertler FB, Hartwig JH, Mullins RD, Brugge JS. Mouneimne G, et al. Among authors: selfors lm. Cancer Cell. 2012 Nov 13;22(5):615-30. doi: 10.1016/j.ccr.2012.09.027. Cancer Cell. 2012. PMID: 23153535 Free PMC article.

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