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Wnt/beta-catenin pathway deregulation in childhood adrenocortical tumors.
Leal LF, Mermejo LM, Ramalho LZ, Martinelli CE Jr, Yunes JA, Seidinger AL, Mastellaro MJ, Cardinalli IA, Brandalise SR, Moreira AC, Tone LG, Scrideli CA, Castro M, Antonini SR. Leal LF, et al. J Clin Endocrinol Metab. 2011 Oct;96(10):3106-14. doi: 10.1210/jc.2011-0363. Epub 2011 Aug 17. J Clin Endocrinol Metab. 2011. PMID: 21849527
Absence of functional LIN28B mutations in a large cohort of patients with idiopathic central precocious puberty.
Silveira-Neto AP, Leal LF, Emerman AB, Henderson KD, Piskounova E, Henderson BE, Gregory RI, Silveira LF, Hirschhorn JN, Nguyen TT, Beneduzzi D, Tusset C, Reis AC, Brito VN, Mendonca BB, Palmert MR, Antonini SR, Latronico AC. Silveira-Neto AP, et al. Among authors: leal lf. Horm Res Paediatr. 2012;78(3):144-50. doi: 10.1159/000342212. Epub 2012 Sep 6. Horm Res Paediatr. 2012. PMID: 22964795 Free PMC article. Clinical Trial.
Sonic hedgehog signaling is active in human adrenal cortex development and deregulated in adrenocortical tumors.
Gomes DC, Leal LF, Mermejo LM, Scrideli CA, Martinelli CE Jr, Fragoso MC, Latronico AC, Tone LG, Tucci S, Yunes JA, Cardinalli IA, Mastellaro MJ, Brandalise SR, Ramalho F, Moreira AC, Ramalho LN, de Castro M, Antonini SR. Gomes DC, et al. Among authors: leal lf. J Clin Endocrinol Metab. 2014 Jul;99(7):E1209-16. doi: 10.1210/jc.2013-4098. Epub 2014 Apr 8. J Clin Endocrinol Metab. 2014. PMID: 24712566
Altered expression of noncanonical Wnt pathway genes in paediatric and adult adrenocortical tumours.
Mermejo LM, Leal LF, Colli LM, Fragoso MC, Latronico AC, Tone LG, Scrideli CA, Tucci S, Martinelli CE, Yunes JA, Mastellaro MJ, Seidinger AL, Brandalise SR, Moreira AC, Ramalho LN, Antonini SR, Castro M. Mermejo LM, et al. Among authors: leal lf. Clin Endocrinol (Oxf). 2014 Oct;81(4):503-10. doi: 10.1111/cen.12462. Epub 2014 May 19. Clin Endocrinol (Oxf). 2014. PMID: 24717047
Sonic Hedgehog pathway is upregulated in adamantinomatous craniopharyngiomas.
Gomes DC, Jamra SA, Leal LF, Colli LM, Campanini ML, Oliveira RS, Martinelli CE Jr, Elias PC, Moreira AC, Machado HR, Saggioro F, Neder L, Castro M, Antonini SR. Gomes DC, et al. Among authors: leal lf. Eur J Endocrinol. 2015 May;172(5):603-8. doi: 10.1530/EJE-14-0934. Epub 2015 Feb 18. Eur J Endocrinol. 2015. PMID: 25693592
IGF2 and IGF1R in pediatric adrenocortical tumors: roles in metastasis and steroidogenesis.
Peixoto Lira RC, Fedatto PF, Marco Antonio DS, Leal LF, Martinelli CE, de Castro M, Tucci S, Neder L, Ramalho L, Seidinger AL, Cardinalli I, Mastellaro MJ, Yunes JA, Brandalise SR, Tone LG, Rauber Antonini SR, Scrideli CA. Peixoto Lira RC, et al. Among authors: leal lf. Endocr Relat Cancer. 2016 Jun;23(6):481-93. doi: 10.1530/ERC-15-0426. Epub 2016 May 16. Endocr Relat Cancer. 2016. PMID: 27185872
Unraveling the expression of the oncogene YAP1, a Wnt/beta-catenin target, in adrenocortical tumors and its association with poor outcome in pediatric patients.
Abduch RH, Carolina Bueno A, Leal LF, Cavalcanti MM, Gomes DC, Brandalise SR, Masterallo MJ, Yunes JA, Martinelli CE Jr, Tone LG, Tucci S, Molina CA, Ramalho FS, Moreira AC, Cardinalli IA, Scrideli CA, Ramalho LN, de Castro M, Antonini SR. Abduch RH, et al. Among authors: leal lf. Oncotarget. 2016 Dec 20;7(51):84634-84644. doi: 10.18632/oncotarget.12382. Oncotarget. 2016. PMID: 27705928 Free PMC article.
66 results