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Zinc-chelating BET bromodomain inhibitors equally target islet endocrine cell types.
Jones Lipinski RA, Stancill JS, Nuñez R, Wynia-Smith SL, Sprague DJ, Nord JA, Bird A, Corbett JA, Smith BC. Jones Lipinski RA, et al. Among authors: sprague dj. Am J Physiol Regul Integr Comp Physiol. 2024 Jun 1;326(6):R515-R527. doi: 10.1152/ajpregu.00259.2023. Epub 2024 Apr 15. Am J Physiol Regul Integr Comp Physiol. 2024. PMID: 38618911
Target-based discovery of a broad spectrum flukicide.
Sprague DJ, Park SK, Gramberg S, Bauer L, Rohr CM, Chulkov EG, Smith E, Scampavia L, Spicer TP, Haeberlein S, Marchant JS. Sprague DJ, et al. bioRxiv [Preprint]. 2023 Sep 22:2023.09.22.559026. doi: 10.1101/2023.09.22.559026. bioRxiv. 2023. PMID: 37790347 Free PMC article. Updated. Preprint.
Target-based discovery of a broad-spectrum flukicide.
Sprague DJ, Park SK, Gramberg S, Bauer L, Rohr CM, Chulkov EG, Smith E, Scampavia L, Spicer TP, Haeberlein S, Marchant JS. Sprague DJ, et al. Nat Struct Mol Biol. 2024 May 7. doi: 10.1038/s41594-024-01298-3. Online ahead of print. Nat Struct Mol Biol. 2024. PMID: 38714890
Identification of a dihydropyridine scaffold that blocks ryanodine receptors.
Gunaratne GS, Rebbeck RT, McGurran LM, Yan Y, Arzua T, Frolkis T, Sprague DJ, Bai X, Cornea RL, Walseth TF, Marchant JS. Gunaratne GS, et al. Among authors: sprague dj. iScience. 2021 Dec 27;25(1):103706. doi: 10.1016/j.isci.2021.103706. eCollection 2022 Jan 21. iScience. 2021. PMID: 35059610 Free PMC article.
23 results