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Segmental Dynamics of Membranous Cholesterol are Coupled.
Della Ripa LA, Courtney JM, Phinney SM, Borcik CG, Burke MD, Rienstra CM, Pogorelov TV. Della Ripa LA, et al. Among authors: burke md. J Am Chem Soc. 2023 Jul 19;145(28):15043-15048. doi: 10.1021/jacs.3c01775. Epub 2023 Jul 6. J Am Chem Soc. 2023. PMID: 37410392
Amphotericin forms an extramembranous and fungicidal sterol sponge.
Anderson TM, Clay MC, Cioffi AG, Diaz KA, Hisao GS, Tuttle MD, Nieuwkoop AJ, Comellas G, Maryum N, Wang S, Uno BE, Wildeman EL, Gonen T, Rienstra CM, Burke MD. Anderson TM, et al. Among authors: burke md. Nat Chem Biol. 2014 May;10(5):400-6. doi: 10.1038/nchembio.1496. Epub 2014 Mar 30. Nat Chem Biol. 2014. PMID: 24681535 Free PMC article.
C3-OH of Amphotericin B Plays an Important Role in Ion Conductance.
Davis SA, Della Ripa LA, Hu L, Cioffi AG, Pogorelov TV, Rienstra CM, Burke MD. Davis SA, et al. Among authors: burke md. J Am Chem Soc. 2015 Dec 9;137(48):15102-4. doi: 10.1021/jacs.5b05766. Epub 2015 Nov 30. J Am Chem Soc. 2015. PMID: 26580003 Free PMC article.
Solid-State NMR of highly 13C-enriched cholesterol in lipid bilayers.
Della Ripa LA, Petros ZA, Cioffi AG, Piehl DW, Courtney JM, Burke MD, Rienstra CM. Della Ripa LA, et al. Among authors: burke md. Methods. 2018 Apr 1;138-139:47-53. doi: 10.1016/j.ymeth.2018.01.008. Epub 2018 Feb 21. Methods. 2018. PMID: 29366688 Free PMC article.
Sterol Sponge Mechanism Is Conserved for Glycosylated Polyene Macrolides.
Guo X, Zhang J, Li X, Xiao E, Lange JD, Rienstra CM, Burke MD, Mitchell DA. Guo X, et al. Among authors: burke md. ACS Cent Sci. 2021 May 26;7(5):781-791. doi: 10.1021/acscentsci.1c00148. Epub 2021 Apr 26. ACS Cent Sci. 2021. PMID: 34079896 Free PMC article.
Fungicidal amphotericin B sponges are assemblies of staggered asymmetric homodimers encasing large void volumes.
Lewandowska A, Soutar CP, Greenwood AI, Nimerovsky E, De Lio AM, Holler JT, Hisao GS, Khandelwal A, Zhang J, SantaMaria AM, Schwieters CD, Pogorelov TV, Burke MD, Rienstra CM. Lewandowska A, et al. Among authors: burke md. Nat Struct Mol Biol. 2021 Dec;28(12):972-981. doi: 10.1038/s41594-021-00685-4. Epub 2021 Dec 9. Nat Struct Mol Biol. 2021. PMID: 34887566 Free PMC article.
Tuning sterol extraction kinetics yields a renal-sparing polyene antifungal.
Maji A, Soutar CP, Zhang J, Lewandowska A, Uno BE, Yan S, Shelke Y, Murhade G, Nimerovsky E, Borcik CG, Arango AS, Lange JD, Marin-Toledo JP, Lyu Y, Bailey KL, Roady PJ, Holler JT, Khandelwal A, SantaMaria AM, Sanchez H, Juvvadi PR, Johns G, Hageman MJ, Krise J, Gebremariam T, Youssef EG, Bartizal K, Marr KA, Steinbach WJ, Ibrahim AS, Patterson TF, Wiederhold NP, Andes DR, Pogorelov TV, Schwieters CD, Fan TM, Rienstra CM, Burke MD. Maji A, et al. Among authors: burke md. Nature. 2023 Nov;623(7989):1079-1085. doi: 10.1038/s41586-023-06710-4. Epub 2023 Nov 8. Nature. 2023. PMID: 37938782 Free PMC article.
281 results