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A FRET-based screening assay for nucleic acid ligands.
Renčiuk D, Zhou J, Beaurepaire L, Guédin A, Bourdoncle A, Mergny JL. Renčiuk D, et al. Among authors: zhou j. Methods. 2012 May;57(1):122-8. doi: 10.1016/j.ymeth.2012.03.020. Epub 2012 Mar 24. Methods. 2012. PMID: 22465278
DNA sequences proximal to human mitochondrial DNA deletion breakpoints prevalent in human disease form G-quadruplexes, a class of DNA structures inefficiently unwound by the mitochondrial replicative Twinkle helicase.
Bharti SK, Sommers JA, Zhou J, Kaplan DL, Spelbrink JN, Mergny JL, Brosh RM Jr. Bharti SK, et al. Among authors: zhou j. J Biol Chem. 2014 Oct 24;289(43):29975-93. doi: 10.1074/jbc.M114.567073. Epub 2014 Sep 5. J Biol Chem. 2014. PMID: 25193669 Free PMC article.
Unexpected Position-Dependent Effects of Ribose G-Quartets in G-Quadruplexes.
Zhou J, Amrane S, Rosu F, Salgado GF, Bian Y, Tateishi-Karimata H, Largy E, Korkut DN, Bourdoncle A, Miyoshi D, Zhang J, Ju H, Wang W, Sugimoto N, Gabelica V, Mergny JL. Zhou J, et al. J Am Chem Soc. 2017 Jun 14;139(23):7768-7779. doi: 10.1021/jacs.7b00648. Epub 2017 Jun 5. J Am Chem Soc. 2017. PMID: 28523907
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