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Loss of the batten disease protein CLN3 leads to mis-trafficking of M6PR and defective autophagic-lysosomal reformation.
Calcagni' A, Staiano L, Zampelli N, Minopoli N, Herz NJ, Di Tullio G, Huynh T, Monfregola J, Esposito A, Cirillo C, Bajic A, Zahabiyon M, Curnock R, Polishchuk E, Parkitny L, Medina DL, Pastore N, Cullen PJ, Parenti G, De Matteis MA, Grumati P, Ballabio A. Calcagni' A, et al. Among authors: herz nj. Nat Commun. 2023 Jul 3;14(1):3911. doi: 10.1038/s41467-023-39643-7. Nat Commun. 2023. PMID: 37400440 Free PMC article.
TFEB regulates murine liver cell fate during development and regeneration.
Pastore N, Huynh T, Herz NJ, Calcagni' A, Klisch TJ, Brunetti L, Kim KH, De Giorgi M, Hurley A, Carissimo A, Mutarelli M, Aleksieva N, D'Orsi L, Lagor WR, Moore DD, Settembre C, Finegold MJ, Forbes SJ, Ballabio A. Pastore N, et al. Among authors: herz nj. Nat Commun. 2020 May 18;11(1):2461. doi: 10.1038/s41467-020-16300-x. Nat Commun. 2020. PMID: 32424153 Free PMC article.
TFE3 regulates whole-body energy metabolism in cooperation with TFEB.
Pastore N, Vainshtein A, Klisch TJ, Armani A, Huynh T, Herz NJ, Polishchuk EV, Sandri M, Ballabio A. Pastore N, et al. Among authors: herz nj. EMBO Mol Med. 2017 May;9(5):605-621. doi: 10.15252/emmm.201607204. EMBO Mol Med. 2017. PMID: 28283651 Free PMC article.