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Anti-myeloma efficacy of CAR-iNKT is enhanced with a long-acting IL-7, rhIL-7-hyFc.
O'Neal J, Cooper ML, Ritchey JK, Gladney S, Niswonger J, González LS, Street E, Haas GJ, Carter A, Amayta PN, Gao F, Lee BH, Choi D, Berrien-Elliott M, Zhou A, Fehniger TA, Rettig MP, DiPersio JF. O'Neal J, et al. Blood Adv. 2023 Oct 24;7(20):6009-6022. doi: 10.1182/bloodadvances.2023010032. Blood Adv. 2023. PMID: 37399471 Free PMC article.
An "off-the-shelf" fratricide-resistant CAR-T for the treatment of T cell hematologic malignancies.
Cooper ML, Choi J, Staser K, Ritchey JK, Devenport JM, Eckardt K, Rettig MP, Wang B, Eissenberg LG, Ghobadi A, Gehrs LN, Prior JL, Achilefu S, Miller CA, Fronick CC, O'Neal J, Gao F, Weinstock DM, Gutierrez A, Fulton RS, DiPersio JF. Cooper ML, et al. Leukemia. 2018 Sep;32(9):1970-1983. doi: 10.1038/s41375-018-0065-5. Epub 2018 Feb 20. Leukemia. 2018. PMID: 29483708 Free PMC article.
A multiple myeloma-specific capture sequencing platform discovers novel translocations and frequent, risk-associated point mutations in IGLL5.
White BS, Lanc I, O'Neal J, Gupta H, Fulton RS, Schmidt H, Fronick C, Belter EA Jr, Fiala M, King J, Ahmann GJ, DeRome M, Mardis ER, Vij R, DiPersio JF, Levy J, Auclair D, Tomasson MH. White BS, et al. Blood Cancer J. 2018 Mar 21;8(3):35. doi: 10.1038/s41408-018-0062-y. Blood Cancer J. 2018. PMID: 29563506 Free PMC article.
VLA4-Targeted Nanoparticles Hijack Cell Adhesion-Mediated Drug Resistance to Target Refractory Myeloma Cells and Prolong Survival.
Fontana F, Scott MJ, Allen JS, Yang X, Cui G, Pan D, Yanaba N, Fiala MA, O'Neal J, Schmieder-Atteberry AH, Ritchey J, Rettig M, Simons K, Fletcher S, Vij R, DiPersio JF, Lanza GM. Fontana F, et al. Clin Cancer Res. 2021 Apr 1;27(7):1974-1986. doi: 10.1158/1078-0432.CCR-20-2839. Epub 2020 Dec 22. Clin Cancer Res. 2021. PMID: 33355244 Free PMC article.
Nanoparticle T-cell engagers as a modular platform for cancer immunotherapy.
Alhallak K, Sun J, Wasden K, Guenthner N, O'Neal J, Muz B, King J, Kohnen D, Vij R, Achilefu S, DiPersio JF, Azab AK. Alhallak K, et al. Leukemia. 2021 Aug;35(8):2346-2357. doi: 10.1038/s41375-021-01127-2. Epub 2021 Jan 21. Leukemia. 2021. PMID: 33479469 Free PMC article.
Co-evolution of tumor and immune cells during progression of multiple myeloma.
Liu R, Gao Q, Foltz SM, Fowles JS, Yao L, Wang JT, Cao S, Sun H, Wendl MC, Sethuraman S, Weerasinghe A, Rettig MP, Storrs EP, Yoon CJ, Wyczalkowski MA, McMichael JF, Kohnen DR, King J, Goldsmith SR, O'Neal J, Fulton RS, Fronick CC, Ley TJ, Jayasinghe RG, Fiala MA, Oh ST, DiPersio JF, Vij R, Ding L. Liu R, et al. Nat Commun. 2021 May 7;12(1):2559. doi: 10.1038/s41467-021-22804-x. Nat Commun. 2021. PMID: 33963182 Free PMC article.
222 results