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DNA-PK is activated by SIRT2 deacetylation to promote DNA double-strand break repair by non-homologous end joining.
Head PE, Kapoor-Vazirani P, Nagaraju GP, Zhang H, Rath SK, Luong NC, Haji-Seyed-Javadi R, Sesay F, Wang SY, Duong DM, Daddacha W, Minten EV, Song B, Danelia D, Liu X, Li S, Ortlund EA, Seyfried NT, Smalley DM, Wang Y, Deng X, Dynan WS, El-Rayes B, Davis AJ, Yu DS. Head PE, et al. Among authors: ortlund ea. Nucleic Acids Res. 2023 Aug 25;51(15):7972-7987. doi: 10.1093/nar/gkad549. Nucleic Acids Res. 2023. PMID: 37395399 Free PMC article.
High-resolution plasma metabolomics analysis to detect Mycobacterium tuberculosis-associated metabolites that distinguish active pulmonary tuberculosis in humans.
Collins JM, Walker DI, Jones DP, Tukvadze N, Liu KH, Tran VT, Uppal K, Frediani JK, Easley KA, Shenvi N, Khadka M, Ortlund EA, Kempker RR, Blumberg HM, Ziegler TR. Collins JM, et al. Among authors: ortlund ea. PLoS One. 2018 Oct 11;13(10):e0205398. doi: 10.1371/journal.pone.0205398. eCollection 2018. PLoS One. 2018. PMID: 30308073 Free PMC article.
Distinct amino acid and lipid perturbations characterize acute versus chronic malaria.
Cordy RJ, Patrapuvich R, Lili LN, Cabrera-Mora M, Chien JT, Tharp GK, Khadka M, Meyer EV, Lapp SA, Joyner CJ, Garcia A, Banton S, Tran V, Luvira V, Rungin S, Saeseu T, Rachaphaew N, Pakala SB, DeBarry JD; MaHPIC Consortium; Kissinger JC, Ortlund EA, Bosinger SE, Barnwell JW, Jones DP, Uppal K, Li S, Sattabongkot J, Moreno A, Galinski MR. Cordy RJ, et al. Among authors: ortlund ea. JCI Insight. 2019 May 2;4(9):e125156. doi: 10.1172/jci.insight.125156. eCollection 2019 May 2. JCI Insight. 2019. PMID: 31045574 Free PMC article.
Caspase-8 Collaborates with Caspase-11 to Drive Tissue Damage and Execution of Endotoxic Shock.
Mandal P, Feng Y, Lyons JD, Berger SB, Otani S, DeLaney A, Tharp GK, Maner-Smith K, Burd EM, Schaeffer M, Hoffman S, Capriotti C, Roback L, Young CB, Liang Z, Ortlund EA, DiPaolo NC, Bosinger S, Bertin J, Gough PJ, Brodsky IE, Coopersmith CM, Shayakhmetov DM, Mocarski ES. Mandal P, et al. Among authors: ortlund ea. Immunity. 2018 Jul 17;49(1):42-55.e6. doi: 10.1016/j.immuni.2018.06.011. Immunity. 2018. PMID: 30021146 Free PMC article.
Resurrection of a functional phosphatidylinositol transfer protein from a pseudo-Sec14 scaffold by directed evolution.
Schaaf G, Dynowski M, Mousley CJ, Shah SD, Yuan P, Winklbauer EM, de Campos MK, Trettin K, Quinones MC, Smirnova TI, Yanagisawa LL, Ortlund EA, Bankaitis VA. Schaaf G, et al. Among authors: ortlund ea. Mol Biol Cell. 2011 Mar 15;22(6):892-905. doi: 10.1091/mbc.E10-11-0903. Epub 2011 Jan 19. Mol Biol Cell. 2011. PMID: 21248202 Free PMC article.
125 results