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Best Practices and Considerations for Clinical Pharmacology and Pharmacometric Aspects for Optimal Development of CAR-T and TCR-T Cell Therapies: An Industry Perspective.
Mody H, Ogasawara K, Zhu X, Miles D, Shastri PN, Gokemeijer J, Liao MZ, Kasichayanula S, Yang TY, Chemuturi N, Gupta S, Jawa V, Upreti VV. Mody H, et al. Among authors: upreti vv. Clin Pharmacol Ther. 2023 Sep;114(3):530-557. doi: 10.1002/cpt.2986. Epub 2023 Jul 26. Clin Pharmacol Ther. 2023. PMID: 37393588 Review.
Dose escalation results from a first-in-human, phase 1 study of glucocorticoid-induced TNF receptor-related protein agonist AMG 228 in patients with advanced solid tumors.
Tran B, Carvajal RD, Marabelle A, Patel SP, LoRusso PM, Rasmussen E, Juan G, Upreti VV, Beers C, Ngarmchamnanrith G, Schöffski P. Tran B, et al. Among authors: upreti vv. J Immunother Cancer. 2018 Sep 25;6(1):93. doi: 10.1186/s40425-018-0407-x. J Immunother Cancer. 2018. PMID: 30253804 Free PMC article. Clinical Trial.
New styryl sulfones as anticancer agents.
Vedula MS, Pulipaka AB, Venna C, Chintakunta VK, Jinnapally S, Kattuboina VA, Vallakati RK, Basetti V, Akella V, Rajgopal S, Reka AK, Teepireddy SK, Mamnoor PK, Rajagopalan R, Bulusu G, Khandelwal A, Upreti VV, Mamidi SR. Vedula MS, et al. Among authors: upreti vv. Eur J Med Chem. 2003 Sep;38(9):811-24. doi: 10.1016/s0223-5234(03)00144-2. Eur J Med Chem. 2003. PMID: 14561480
VN/14-1 induces ER stress and autophagy in HP-LTLC human breast cancer cells and has excellent oral pharmacokinetic profile in female Sprague Dawley rats.
Godbole AM, Ramalingam S, Ramamurthy VP, Khandelwal A, Bruno RD, Upreti VV, Gediya LK, Purushottamachar P, Mbatia HW, Addya S, Ambulos N, Njar VC. Godbole AM, et al. Among authors: upreti vv. Eur J Pharmacol. 2014 Jul 5;734:98-104. doi: 10.1016/j.ejphar.2014.04.004. Epub 2014 Apr 12. Eur J Pharmacol. 2014. PMID: 24726842 Free PMC article.
50 results