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Page 1
Discovery of PLpro and Mpro Inhibitors for SARS-CoV-2.
Puhl AC, Godoy AS, Noske GD, Nakamura AM, Gawriljuk VO, Fernandes RS, Oliva G, Ekins S. Puhl AC, et al. ACS Omega. 2023 Jun 14;8(25):22603-22612. doi: 10.1021/acsomega.3c01110. eCollection 2023 Jun 27. ACS Omega. 2023. PMID: 37387790 Free PMC article.
Design of amidobenzimidazole STING receptor agonists with systemic activity.
Ramanjulu JM, Pesiridis GS, Yang J, Concha N, Singhaus R, Zhang SY, Tran JL, Moore P, Lehmann S, Eberl HC, Muelbaier M, Schneck JL, Clemens J, Adam M, Mehlmann J, Romano J, Morales A, Kang J, Leister L, Graybill TL, Charnley AK, Ye G, Nevins N, Behnia K, Wolf AI, Kasparcova V, Nurse K, Wang L, Puhl AC, Li Y, Klein M, Hopson CB, Guss J, Bantscheff M, Bergamini G, Reilly MA, Lian Y, Duffy KJ, Adams J, Foley KP, Gough PJ, Marquis RW, Smothers J, Hoos A, Bertin J. Ramanjulu JM, et al. Among authors: puhl ac. Nature. 2018 Dec;564(7736):439-443. doi: 10.1038/s41586-018-0705-y. Epub 2018 Nov 7. Nature. 2018. PMID: 30405246
Crystallographic structure and molecular dynamics simulations of the major endoglucanase from Xanthomonas campestris pv. campestris shed light on its oligosaccharide products release pattern.
Puhl AC, Prates ET, Rosseto FR, Manzine LR, Stankovic I, de Araújo SS, Alvarez TM, Squina FM, Skaf MS, Polikarpov I. Puhl AC, et al. Int J Biol Macromol. 2019 Sep 1;136:493-502. doi: 10.1016/j.ijbiomac.2019.06.107. Epub 2019 Jun 16. Int J Biol Macromol. 2019. PMID: 31216447
Author Correction: Design of amidobenzimidazole STING receptor agonists with systemic activity.
Ramanjulu JM, Pesiridis GS, Yang J, Concha N, Singhaus R, Zhang SY, Tran JL, Moore P, Lehmann S, Eberl HC, Muelbaier M, Schneck JL, Clemens J, Adam M, Mehlmann J, Romano J, Morales A, Kang J, Leister L, Graybill TL, Charnley AK, Ye G, Nevins N, Behnia K, Wolf AI, Kasparcova V, Nurse K, Wang L, Puhl AC, Li Y, Klein M, Hopson CB, Guss J, Bantscheff M, Bergamini G, Reilly MA, Lian Y, Duffy KJ, Adams J, Foley KP, Gough PJ, Marquis RW, Smothers J, Hoos A, Bertin J. Ramanjulu JM, et al. Among authors: puhl ac. Nature. 2019 Jun;570(7761):E53. doi: 10.1038/s41586-019-1265-5. Nature. 2019. PMID: 31142845
Crystallization and preliminary diffraction analysis of the catalytic domain of major extracellular endoglucanase from Xanthomonas campestris pv. campestris.
Rosseto FR, Puhl AC, Andrade MO, Polikarpov I. Rosseto FR, et al. Among authors: puhl ac. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Feb 1;69(Pt 2):137-40. doi: 10.1107/S1744309112051408. Epub 2013 Jan 31. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013. PMID: 23385754 Free PMC article.
New targets for HIV drug discovery.
Puhl AC, Garzino Demo A, Makarov VA, Ekins S. Puhl AC, et al. Drug Discov Today. 2019 May;24(5):1139-1147. doi: 10.1016/j.drudis.2019.03.013. Epub 2019 Mar 15. Drug Discov Today. 2019. PMID: 30885676 Free PMC article. Review.
Déjà vu: Stimulating open drug discovery for SARS-CoV-2.
Ekins S, Mottin M, Ramos PRPS, Sousa BKP, Neves BJ, Foil DH, Zorn KM, Braga RC, Coffee M, Southan C, Puhl AC, Andrade CH. Ekins S, et al. Among authors: puhl ac. Drug Discov Today. 2020 May;25(5):928-941. doi: 10.1016/j.drudis.2020.03.019. Epub 2020 Apr 19. Drug Discov Today. 2020. PMID: 32320852 Free PMC article. Review.
48 results