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AXL Inhibition Improves the Antitumor Activity of Chimeric Antigen Receptor T Cells.
Sakemura RL, Hefazi M, Cox MJ, Siegler EL, Sinha S, Hansen MJ, Stewart CM, Feigin JM, Manriquez Roman C, Schick KJ, Can I, Tapper EE, Horvei P, Adada MM, Bezerra ED, Kankeu Fonkoua LA, Ruff MW, Forsman CL, Nevala WK, Boysen JC, Tschumper RC, Grand CL, Kuchimanchi KR, Mouritsen L, Foulks JM, Warner SL, Call TG, Parikh SA, Ding W, Kay NE, Kenderian SS. Sakemura RL, et al. Among authors: boysen jc. Cancer Immunol Res. 2023 Sep 1;11(9):1222-1236. doi: 10.1158/2326-6066.CIR-22-0254. Cancer Immunol Res. 2023. PMID: 37378662 Free PMC article.
Chronic lymphocytic leukemia cells from ibrutinib treated patients are sensitive to Axl receptor tyrosine kinase inhibitor therapy.
Sinha S, Boysen JC, Chaffee KG, Kabat BF, Slager SL, Parikh SA, Secreto CR, Call T, Shanafelt TD, Leis JF, Warner SL, Bearss DJ, Ghosh AK, Kay NE. Sinha S, et al. Among authors: boysen jc. Oncotarget. 2018 Dec 14;9(98):37173-37184. doi: 10.18632/oncotarget.26444. eCollection 2018 Dec 14. Oncotarget. 2018. PMID: 30647852 Free PMC article.
Leukemic extracellular vesicles induce chimeric antigen receptor T cell dysfunction in chronic lymphocytic leukemia.
Cox MJ, Lucien F, Sakemura R, Boysen JC, Kim Y, Horvei P, Manriquez Roman C, Hansen MJ, Tapper EE, Siegler EL, Forsman C, Crotts SB, Schick KJ, Hefazi M, Ruff MW, Can I, Adada M, Bezerra E, Kankeu Fonkoua LA, Nevala WK, Braggio E, Ding W, Parikh SA, Kay NE, Kenderian SS. Cox MJ, et al. Among authors: boysen jc. Mol Ther. 2021 Apr 7;29(4):1529-1540. doi: 10.1016/j.ymthe.2020.12.033. Epub 2021 Jan 1. Mol Ther. 2021. PMID: 33388419 Free PMC article.
Upregulation of AXL and β-catenin in chronic lymphocytic leukemia cells cultured with bone marrow stroma cells is associated with enhanced drug resistance.
Sinha S, Secreto CR, Boysen JC, Lesnick C, Wang Z, Ding W, Call TG, Kenderian SJ, Parikh SA, Warner SL, Bearss DJ, Ghosh AK, Kay NE. Sinha S, et al. Among authors: boysen jc. Blood Cancer J. 2021 Feb 18;11(2):37. doi: 10.1038/s41408-021-00426-2. Blood Cancer J. 2021. PMID: 33602892 Free PMC article. No abstract available.
Platelet-derived growth factor (PDGF)-PDGF receptor interaction activates bone marrow-derived mesenchymal stromal cells derived from chronic lymphocytic leukemia: implications for an angiogenic switch.
Ding W, Knox TR, Tschumper RC, Wu W, Schwager SM, Boysen JC, Jelinek DF, Kay NE. Ding W, et al. Among authors: boysen jc. Blood. 2010 Oct 21;116(16):2984-93. doi: 10.1182/blood-2010-02-269894. Epub 2010 Jul 6. Blood. 2010. PMID: 20606160 Free PMC article.
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