Luo D - Search Results

1

Discovery of a Potent Highly Biased MOR Partial Agonist among Diastereomeric C9-Hydroxyalkyl-5-phenylmorphans.

Lutz JA, Sulima A, Gutman ES, Bow EW, Luo D, Kaska S, Prisinzano TE, Paronis CA, Bergman J, Imler GH, Kerr AT, Jacobson AE, Rice KC. Lutz JA, et al. Among authors: luo d. Molecules. 2023 Jun 15;28(12):4795. doi: 10.3390/molecules28124795. Molecules. 2023. PMID: 37375350 Free PMC article.

2

Synthetic Studies of Neoclerodane Diterpenes from Salvia divinorum: Design, Synthesis, and Evaluation of Analogues with Improved Potency and G-protein Activation Bias at the μ-Opioid Receptor.

Crowley RS, Riley AP, Alder AF, Anderson RJ 3rd, Luo D, Kaska S, Maynez P, Kivell BM, Prisinzano TE. Crowley RS, et al. Among authors: luo d. ACS Chem Neurosci. 2020 Jun 17;11(12):1781-1790. doi: 10.1021/acschemneuro.0c00191. Epub 2020 May 26. ACS Chem Neurosci. 2020. PMID: 32383854 Free PMC article.

3

Design, synthesis, and preliminary evaluation of a potential synthetic opioid rescue agent.

Hedrick SL, Luo D, Kaska S, Niloy KK, Jackson K, Sarma R, Horn J, Baynard C, Leggas M, Butelman ER, Kreek MJ, Prisinzano TE. Hedrick SL, et al. Among authors: luo d. J Biomed Sci. 2021 Sep 9;28(1):62. doi: 10.1186/s12929-021-00758-y. J Biomed Sci. 2021. PMID: 34503531 Free PMC article.

4

Structure-activity studies of PTPRD phosphatase inhibitors identify a 7-cyclopentymethoxy illudalic acid analog candidate for development.

Henderson IM, Zeng F, Bhuiyan NH, Luo D, Martinez M, Smoake J, Bi F, Perera C, Johnson D, Prisinzano TE, Wang W, Uhl GR. Henderson IM, et al. Among authors: luo d. Biochem Pharmacol. 2022 Jan;195:114868. doi: 10.1016/j.bcp.2021.114868. Epub 2021 Dec 2. Biochem Pharmacol. 2022. PMID: 34863978 Free PMC article.

5

The Salvinorin Analogue, Ethoxymethyl Ether Salvinorin B, Promotes Remyelination in Preclinical Models of Multiple Sclerosis.

Paton KF, Robichon K, Templeton N, Denny L, Al Abadey A, Luo D, Prisinzano TE, La Flamme AC, Kivell BM. Paton KF, et al. Among authors: luo d. Front Neurol. 2021 Dec 20;12:782190. doi: 10.3389/fneur.2021.782190. eCollection 2021. Front Neurol. 2021. PMID: 34987466 Free PMC article.

6

Sex Differences in Kappa Opioid Receptor Agonist Mediated Attenuation of Chemotherapy-Induced Neuropathic Pain in Mice.

Paton KF, Luo D, La Flamme AC, Prisinzano TE, Kivell BM. Paton KF, et al. Among authors: luo d. Front Pharmacol. 2022 Feb 18;13:813562. doi: 10.3389/fphar.2022.813562. eCollection 2022. Front Pharmacol. 2022. PMID: 35250563 Free PMC article.

7

A Journey through Diastereomeric Space: The Design, Synthesis, In Vitro and In Vivo Pharmacological Activity, and Molecular Modeling of Novel Potent Diastereomeric MOR Agonists and Antagonists.

Chambers DR, Sulima A, Luo D, Prisinzano TE, Goldberg A, Xie B, Shi L, Paronis CA, Bergman J, Nassehi N, Selley DE, Imler GH, Jacobson AE, Rice KC. Chambers DR, et al. Among authors: luo d. Molecules. 2022 Sep 30;27(19):6455. doi: 10.3390/molecules27196455. Molecules. 2022. PMID: 36234992 Free PMC article.

8

Synthesis and Pharmacological Evaluation of Enantiopure N-Substituted Ortho-c Oxide-Bridged 5-Phenylmorphans.

Li F, Kopajtic TA, Katz JL, Luo D, Prisinzano TE, Imler GH, Deschamps JR, Jacobson AE, Rice KC. Li F, et al. Among authors: luo d. Molecules. 2022 Dec 12;27(24):8808. doi: 10.3390/molecules27248808. Molecules. 2022. PMID: 36557961 Free PMC article.

9

Xylazine suppresses fentanyl consumption during self-administration and induces a unique sex-specific withdrawal syndrome that is not altered by naloxone in rats.

Khatri SN, Sadek S, Kendrick PT, Bondy EO, Hong M, Pauss S, Luo D, Prisinzano TE, Dunn KE, Marusich JA, Beckmann JS, Hinds TD, Gipson CD. Khatri SN, et al. Among authors: luo d. Exp Clin Psychopharmacol. 2024 Apr;32(2):150-157. doi: 10.1037/pha0000670. Epub 2023 Jul 20. Exp Clin Psychopharmacol. 2024. PMID: 37470999

10

A MOR Antagonist with High Potency and Antagonist Efficacy among Diastereomeric C9-Alkyl-Substituted N-Phenethyl-5-(3-hydroxy)phenylmorphans.

Chambers DR, Sulima A, Luo D, Prisinzano TE, Jacobson AE, Rice KC. Chambers DR, et al. Among authors: luo d. Molecules. 2023 Jul 14;28(14):5411. doi: 10.3390/molecules28145411. Molecules. 2023. PMID: 37513283 Free PMC article.

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