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DAPTA, a C-C Chemokine Receptor 5 (CCR5), Leads to the Downregulation of Notch/NF-κB Signaling and Proinflammatory Mediators in CD40+ Cells in Experimental Autoimmune Encephalomyelitis Model in SJL/J Mice.
Alghibiwi H, Ansari MA, Nadeem A, Algonaiah MA, Attia SM, Bakheet SA, Albekairi TH, Almudimeegh S, Alhamed AS, Shahid M, Alwetaid MY, Alassmrry YA, Ahmad SF. Alghibiwi H, et al. Among authors: almudimeegh s. Biomedicines. 2023 May 23;11(6):1511. doi: 10.3390/biomedicines11061511. Biomedicines. 2023. PMID: 37371605 Free PMC article.
Mitogen-activated protein kinase inhibitor PD98059 improves neuroimmune dysfunction in experimental autoimmune encephalomyelitis in SJL/J mice through the inhibition of nuclear factor-kappa B signaling in B cells.
Alomar HA, Nadeem A, Ansari MA, Attia SM, Bakheet SA, Al-Mazroua HA, Alhazzani K, Assiri MA, Alqinyah M, Almudimeegh S, Ahmad SF. Alomar HA, et al. Among authors: almudimeegh s. Brain Res Bull. 2023 Mar;194:45-53. doi: 10.1016/j.brainresbull.2023.01.003. Epub 2023 Jan 13. Brain Res Bull. 2023. PMID: 36646144 Free article.
Clinical, genetic, and functional characterization of the glycine receptor β-subunit A455P variant in a family affected by hyperekplexia syndrome.
Aboheimed GI, AlRasheed MM, Almudimeegh S, Peña-Guerra KA, Cardona-Londoño KJ, Salih MA, Seidahmed MZ, Al-Mohanna F, Colak D, Harvey RJ, Harvey K, Arold ST, Kaya N, Ruiz AJ. Aboheimed GI, et al. Among authors: almudimeegh s. J Biol Chem. 2022 Jul;298(7):102018. doi: 10.1016/j.jbc.2022.102018. Epub 2022 May 6. J Biol Chem. 2022. PMID: 35526563 Free PMC article.
Downregulated Wnt/β-catenin signalling in the Down syndrome hippocampus.
Granno S, Nixon-Abell J, Berwick DC, Tosh J, Heaton G, Almudimeegh S, Nagda Z, Rain JC, Zanda M, Plagnol V, Tybulewicz VLJ, Cleverley K, Wiseman FK, Fisher EMC, Harvey K. Granno S, et al. Among authors: almudimeegh s. Sci Rep. 2019 May 13;9(1):7322. doi: 10.1038/s41598-019-43820-4. Sci Rep. 2019. PMID: 31086297 Free PMC article.