McGeary RP - Search Results

1

Inhibitors for metallo-β-lactamases from the B1 and B3 subgroups provide an avenue to combat a major mechanism of antibiotic resistance.

Kurz JL, Pedroso MM, Richard E, McGeary RP, Schenk G. Kurz JL, et al. Among authors: mcgeary rp. Bioorg Med Chem Lett. 2023 Aug 15;92:129387. doi: 10.1016/j.bmcl.2023.129387. Epub 2023 Jun 25. Bioorg Med Chem Lett. 2023. PMID: 37369333 Free article.

2

3-mercapto-1,2,4-triazoles and N-acylated thiosemicarbazides as metallo-β-lactamase inhibitors.

Faridoon, Hussein WM, Vella P, Islam NU, Ollis DL, Schenk G, McGeary RP. Faridoon, et al. Among authors: mcgeary rp. Bioorg Med Chem Lett. 2012 Jan 1;22(1):380-6. doi: 10.1016/j.bmcl.2011.10.116. Epub 2011 Nov 6. Bioorg Med Chem Lett. 2012. PMID: 22115595

3

The applications of binuclear metallohydrolases in medicine: recent advances in the design and development of novel drug leads for purple acid phosphatases, metallo-β-lactamases and arginases.

McGeary RP, Schenk G, Guddat LW. McGeary RP, et al. Eur J Med Chem. 2014 Apr 9;76:132-44. doi: 10.1016/j.ejmech.2014.02.008. Epub 2014 Feb 8. Eur J Med Chem. 2014. PMID: 24583353 Review.

4

Captopril analogues as metallo-β-lactamase inhibitors.

Yusof Y, Tan DTC, Arjomandi OK, Schenk G, McGeary RP. Yusof Y, et al. Among authors: mcgeary rp. Bioorg Med Chem Lett. 2016 Mar 15;26(6):1589-1593. doi: 10.1016/j.bmcl.2016.02.007. Epub 2016 Feb 4. Bioorg Med Chem Lett. 2016. PMID: 26883147

5

Progress toward inhibitors of metallo-β-lactamases.

McGeary RP, Tan DT, Schenk G. McGeary RP, et al. Future Med Chem. 2017 May;9(7):673-691. doi: 10.4155/fmc-2017-0007. Epub 2017 May 15. Future Med Chem. 2017. PMID: 28504895 Review.

6

Structure-activity relationship study and optimisation of 2-aminopyrrole-1-benzyl-4,5-diphenyl-1H-pyrrole-3-carbonitrile as a broad spectrum metallo-β-lactamase inhibitor.

McGeary RP, Tan DTC, Selleck C, Monteiro Pedroso M, Sidjabat HE, Schenk G. McGeary RP, et al. Eur J Med Chem. 2017 Sep 8;137:351-364. doi: 10.1016/j.ejmech.2017.05.061. Epub 2017 Jun 3. Eur J Med Chem. 2017. PMID: 28614759

7

Inhibition of purple acid phosphatase with alpha-alkoxynaphthylmethylphosphonic acids.

McGeary RP, Vella P, Mak JY, Guddat LW, Schenk G. McGeary RP, et al. Bioorg Med Chem Lett. 2009 Jan 1;19(1):163-6. doi: 10.1016/j.bmcl.2008.10.125. Epub 2008 Nov 5. Bioorg Med Chem Lett. 2009. PMID: 19010677

8

Synthesis, modelling and kinetic assays of potent inhibitors of purple acid phosphatase.

Mohd-Pahmi SH, Hussein WM, Schenk G, McGeary RP. Mohd-Pahmi SH, et al. Among authors: mcgeary rp. Bioorg Med Chem Lett. 2011 May 15;21(10):3092-4. doi: 10.1016/j.bmcl.2011.03.024. Epub 2011 Mar 13. Bioorg Med Chem Lett. 2011. PMID: 21459576

9

The identification of new metallo-β-lactamase inhibitor leads from fragment-based screening.

Vella P, Hussein WM, Leung EW, Clayton D, Ollis DL, Mitić N, Schenk G, McGeary RP. Vella P, et al. Among authors: mcgeary rp. Bioorg Med Chem Lett. 2011 Jun 1;21(11):3282-5. doi: 10.1016/j.bmcl.2011.04.027. Epub 2011 Apr 13. Bioorg Med Chem Lett. 2011. PMID: 21536436

10

Penicillin inhibitors of purple acid phosphatase.

Faridoon, Hussein WM, Ul Islam N, Guddat LW, Schenk G, McGeary RP. Faridoon, et al. Among authors: mcgeary rp. Bioorg Med Chem Lett. 2012 Apr 1;22(7):2555-9. doi: 10.1016/j.bmcl.2012.01.123. Epub 2012 Feb 4. Bioorg Med Chem Lett. 2012. PMID: 22366658

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