Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

26,221 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Tyrosinase deficiency impairs social novelty preference in mice.
Aizawa S, Yamamuro Y. Aizawa S, et al. Neuroreport. 2024 May 30. doi: 10.1097/WNR.0000000000002055. Online ahead of print. Neuroreport. 2024. PMID: 38829918
We also found that the hippocampal expression of genes involved in catecholamine metabolism, such as monoamine oxidase A and catechol-O-methyltransferase, were significantly decreased in tyrosinase-deficient B10-c mice. ...
We also found that the hippocampal expression of genes involved in catecholamine metabolism, such as monoamine oxidase A and c …
Targeting Biometals in Alzheimer's Disease with Metal Chelating Agents Including Coumarin Derivatives.
Gucký A, Hamuľaková S. Gucký A, et al. CNS Drugs. 2024 Jun 3. doi: 10.1007/s40263-024-01093-0. Online ahead of print. CNS Drugs. 2024. PMID: 38829443 Review.
Various coumarin derivatives match this description and apart from being able to chelate metal ions, they exhibit the capacity to inhibit cholinesterases (ChEs) and monoamine oxidase B (MAO-B) while also possessing antioxidant, anti-inflammatory, and numerous other …
Various coumarin derivatives match this description and apart from being able to chelate metal ions, they exhibit the capacity to inhibit ch …
Computational identification of potential acetylcholinesterase (AChE) and monoamine oxidase-B inhibitors from Vitis vinifera: a case study of Alzheimer's disease (AD).
Sofela SO, Ibrahim A, Ogbodo UC, Bodun DS, Nwankwo DO, Mafimisebi M, Abdulrasheed B, Balogun T, Opeyemi I. Sofela SO, et al. In Silico Pharmacol. 2024 May 31;12(1):49. doi: 10.1007/s40203-024-00214-3. eCollection 2024. In Silico Pharmacol. 2024. PMID: 38828442
At the same time, the currently available anti-cholinesterase (AChE) and monoamine oxidase-B (MAO-B) for the treatment of AD can only improve the clinical symptoms while the recently approved immunotherapy agent "remains questionable. ...
At the same time, the currently available anti-cholinesterase (AChE) and monoamine oxidase-B (MAO-B) for the treatment of AD c …
Pharmacological and behavioural effects of tryptamines present in psilocybin-containing mushrooms.
Rakoczy RJ, Runge GN, Sen AK, Sandoval O, Wells HG, Nguyen Q, Roberts BR, Sciortino JH, Gibbons WJ Jr, Friedberg LM, Jones JA, McMurray MS. Rakoczy RJ, et al. Br J Pharmacol. 2024 Jun 2. doi: 10.1111/bph.16466. Online ahead of print. Br J Pharmacol. 2024. PMID: 38825326
KEY RESULTS: In vitro enzyme kinetics assays found that all compounds had nearly identical rates of dephosphorylation via alkaline phosphatase and metabolism by monoamine oxidase. Further, we found that only the dephosphorylated products of baeocystin and norbaeocys …
KEY RESULTS: In vitro enzyme kinetics assays found that all compounds had nearly identical rates of dephosphorylation via alkaline phosphata …
Non-cytotoxic 3-Acetylcoumarin as an Attractive Target for Human Monoamine Oxidase (HMAO) Enzymes.
Aghimien MO, Kolawole Q, Igbinoba PO, Musa MA, Latinwo L. Aghimien MO, et al. Anticancer Res. 2024 Jun;44(6):2335-2341. doi: 10.21873/anticanres.17040. Anticancer Res. 2024. PMID: 38821578
BACKGROUND/AIM: Coumarins are a broad class of naturally occurring oxygen-heterocyclic compounds found in plants with diverse biological properties, making them attractive for evaluation as novel therapeutic agents. We herein report the in vitro cytotoxic and monoamine …
BACKGROUND/AIM: Coumarins are a broad class of naturally occurring oxygen-heterocyclic compounds found in plants with diverse biological pro …
Design and discovery of anthranilamide derivatives as a potential treatment for neurodegenerative disorders via targeting cholinesterases and monoamine oxidases.
Zaib S, Khan I, Ali HS, Younas MT, Ibrar A, Al-Odayni AB, Al-Kahtani AA. Zaib S, et al. Int J Biol Macromol. 2024 May 29:132748. doi: 10.1016/j.ijbiomac.2024.132748. Online ahead of print. Int J Biol Macromol. 2024. PMID: 38821306
Several other compounds were found as highly potent and selective inhibitors. Anthranilamide derivatives were also tested against monoamine oxidase (A and B) enzymes using fluorometric method. In vitro data revealed compound 6h as the most potent inhibitor against …
Several other compounds were found as highly potent and selective inhibitors. Anthranilamide derivatives were also tested against monoami …
Dietary supplement for mood symptoms in early postpartum: a double-blind randomized placebo controlled trial.
Meyer JH, Wang Z, Santhirakumar A, Dowlati Y, Docteur N, Shoaib A, Purnava J, Wang Y, Wang W, Chen S, Husain MI, de Silva Wijeyeratne R, Reeyaz H, Baena-Tan C, Koshimori Y, Nasser Z, Sit V. Meyer JH, et al. EClinicalMedicine. 2024 Apr 10;71:102593. doi: 10.1016/j.eclinm.2024.102593. eCollection 2024 May. EClinicalMedicine. 2024. PMID: 38813444 Free PMC article.
The supplement was designed to counter downstream effects of elevated monoamine oxidase A level, implicated in causing PPB. METHODS: Participants recruited by advertisement from the Toronto region completed procedures at CAMH, Canada and/or participants' homes. ...
The supplement was designed to counter downstream effects of elevated monoamine oxidase A level, implicated in causing PPB. ME …
Comprehensive safety evaluation of a novel multitargeting compound XYY-CP1106: A candidate for Alzheimer's disease.
Fan M, Song X, Lu L, He J, Shen Y, Zhang C, Wang F, Xie Y. Fan M, et al. Biomed Pharmacother. 2024 May 27;176:116786. doi: 10.1016/j.biopha.2024.116786. Online ahead of print. Biomed Pharmacother. 2024. PMID: 38805971 Free article.
Here, the safety evaluation of a novel multi-targeted candidate in AD (XYY-CP1106), characterized by its dual-property of iron chelation and monoamine oxidase B inhibition, was conducted by multifaceted analysis. ...
Here, the safety evaluation of a novel multi-targeted candidate in AD (XYY-CP1106), characterized by its dual-property of iron chelation and …
Neurotoxic effects of carbamazepine on the mosquitofish Gambusia affinis.
Nikhil J, Maneesha P, Chitra KC. Nikhil J, et al. Drug Chem Toxicol. 2024 May 28:1-15. doi: 10.1080/01480545.2024.2356048. Online ahead of print. Drug Chem Toxicol. 2024. PMID: 38804213
Furthermore, the neurotoxic effects of carbamazepine were clearly demonstrated through alterations in various neurological parameters, including acetylcholinesterase, dopamine, gamma-aminobutyric acid, serotonin, monoamine oxidase, 5-hydroxyindole acetic acid, adren …
Furthermore, the neurotoxic effects of carbamazepine were clearly demonstrated through alterations in various neurological parameters, inclu …
26,221 results
You have reached the last available page of results. Please see the User Guide for more information.