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Generation of a humanized Aβ expressing mouse demonstrating aspects of Alzheimer's disease-like pathology.
Baglietto-Vargas D, Forner S, Cai L, Martini AC, Trujillo-Estrada L, Swarup V, Nguyen MMT, Do Huynh K, Javonillo DI, Tran KM, Phan J, Jiang S, Kramár EA, Nuñez-Diaz C, Balderrama-Gutierrez G, Garcia F, Childs J, Rodriguez-Ortiz CJ, Garcia-Leon JA, Kitazawa M, Shahnawaz M, Matheos DP, Ma X, Da Cunha C, Walls KC, Ager RR, Soto C, Gutierrez A, Moreno-Gonzalez I, Mortazavi A, Tenner AJ, MacGregor GR, Wood M, Green KN, LaFerla FM. Baglietto-Vargas D, et al. Among authors: green kn. Nat Commun. 2021 Apr 23;12(1):2421. doi: 10.1038/s41467-021-22624-z. Nat Commun. 2021. PMID: 33893290 Free PMC article.
Systematic phenotyping and characterization of the 5xFAD mouse model of Alzheimer's disease.
Forner S, Kawauchi S, Balderrama-Gutierrez G, Kramár EA, Matheos DP, Phan J, Javonillo DI, Tran KM, Hingco E, da Cunha C, Rezaie N, Alcantara JA, Baglietto-Vargas D, Jansen C, Neumann J, Wood MA, MacGregor GR, Mortazavi A, Tenner AJ, LaFerla FM, Green KN. Forner S, et al. Among authors: green kn. Sci Data. 2021 Oct 15;8(1):270. doi: 10.1038/s41597-021-01054-y. Sci Data. 2021. PMID: 34654824 Free PMC article.
Microglia do not restrict SARS-CoV-2 replication following infection of the central nervous system of K18-hACE2 transgenic mice.
Olivarria GM, Cheng Y, Furman S, Pachow C, Hohsfield LA, Smith-Geater C, Miramontes R, Wu J, Burns MS, Tsourmas KI, Stocksdale J, Manlapaz C, Yong WH, Teijaro J, Edwards R, Green KN, Thompson LM, Lane TE. Olivarria GM, et al. Among authors: green kn. bioRxiv [Preprint]. 2021 Nov 17:2021.11.15.468761. doi: 10.1101/2021.11.15.468761. bioRxiv. 2021. PMID: 34816260 Free PMC article. Updated. Preprint.
Microglia Do Not Restrict SARS-CoV-2 Replication following Infection of the Central Nervous System of K18-Human ACE2 Transgenic Mice.
Olivarria GM, Cheng Y, Furman S, Pachow C, Hohsfield LA, Smith-Geater C, Miramontes R, Wu J, Burns MS, Tsourmas KI, Stocksdale J, Manlapaz C, Yong WH, Teijaro J, Edwards R, Green KN, Thompson LM, Lane TE. Olivarria GM, et al. Among authors: green kn. J Virol. 2022 Feb 23;96(4):e0196921. doi: 10.1128/jvi.01969-21. Epub 2021 Dec 22. J Virol. 2022. PMID: 34935438 Free PMC article.
Systematic Phenotyping and Characterization of the 3xTg-AD Mouse Model of Alzheimer's Disease.
Javonillo DI, Tran KM, Phan J, Hingco E, Kramár EA, da Cunha C, Forner S, Kawauchi S, Milinkeviciute G, Gomez-Arboledas A, Neumann J, Banh CE, Huynh M, Matheos DP, Rezaie N, Alcantara JA, Mortazavi A, Wood MA, Tenner AJ, MacGregor GR, Green KN, LaFerla FM. Javonillo DI, et al. Among authors: green kn. Front Neurosci. 2022 Jan 24;15:785276. doi: 10.3389/fnins.2021.785276. eCollection 2021. Front Neurosci. 2022. PMID: 35140584 Free PMC article.
Frequent Low-Dose Δ9-Tetrahydrocannabinol in Adolescence Disrupts Microglia Homeostasis and Disables Responses to Microbial Infection and Social Stress in Young Adulthood.
Lee HL, Jung KM, Fotio Y, Squire E, Palese F, Lin L, Torrens A, Ahmed F, Mabou Tagne A, Ramirez J, Su S, Wong CR, Jung DH, Scarfone VM, Nguyen PU, Wood M, Green K, Piomelli D. Lee HL, et al. Biol Psychiatry. 2022 Dec 1;92(11):845-860. doi: 10.1016/j.biopsych.2022.04.017. Epub 2022 May 10. Biol Psychiatry. 2022. PMID: 35750512 Free PMC article.
A Trem2R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaques.
Tran KM, Kawauchi S, Kramár EA, Rezaie N, Liang HY, Sakr JS, Gomez-Arboledas A, Arreola MA, Cunha CD, Phan J, Wang S, Collins S, Walker A, Shi KX, Neumann J, Filimban G, Shi Z, Milinkeviciute G, Javonillo DI, Tran K, Gantuz M, Forner S, Swarup V, Tenner AJ, LaFerla FM, Wood MA, Mortazavi A, MacGregor GR, Green KN. Tran KM, et al. Among authors: green kn. Mol Neurodegener. 2023 Feb 17;18(1):12. doi: 10.1186/s13024-023-00598-4. Mol Neurodegener. 2023. PMID: 36803190 Free PMC article.
164 results