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Downregulation of robust acute type I interferon responses distinguishes nonpathogenic simian immunodeficiency virus (SIV) infection of natural hosts from pathogenic SIV infection of rhesus macaques.
Harris LD, Tabb B, Sodora DL, Paiardini M, Klatt NR, Douek DC, Silvestri G, Müller-Trutwin M, Vasile-Pandrea I, Apetrei C, Hirsch V, Lifson J, Brenchley JM, Estes JD. Harris LD, et al. Among authors: brenchley jm. J Virol. 2010 Aug;84(15):7886-91. doi: 10.1128/JVI.02612-09. Epub 2010 May 19. J Virol. 2010. PMID: 20484518 Free PMC article.
Depletion of CD4⁺ T cells abrogates post-peak decline of viremia in SIV-infected rhesus macaques.
Ortiz AM, Klatt NR, Li B, Yi Y, Tabb B, Hao XP, Sternberg L, Lawson B, Carnathan PM, Cramer EM, Engram JC, Little DM, Ryzhova E, Gonzalez-Scarano F, Paiardini M, Ansari AA, Ratcliffe S, Else JG, Brenchley JM, Collman RG, Estes JD, Derdeyn CA, Silvestri G. Ortiz AM, et al. Among authors: brenchley jm. J Clin Invest. 2011 Nov;121(11):4433-45. doi: 10.1172/JCI46023. Epub 2011 Oct 17. J Clin Invest. 2011. PMID: 22005304 Free PMC article.
Dynamics of simian immunodeficiency virus SIVmac239 infection in pigtail macaques.
Klatt NR, Canary LA, Vanderford TH, Vinton CL, Engram JC, Dunham RM, Cronise HE, Swerczek JM, Lafont BA, Picker LJ, Silvestri G, Brenchley JM. Klatt NR, et al. Among authors: brenchley jm. J Virol. 2012 Jan;86(2):1203-13. doi: 10.1128/JVI.06033-11. Epub 2011 Nov 16. J Virol. 2012. PMID: 22090099 Free PMC article.
Loss of mucosal CD103+ DCs and IL-17+ and IL-22+ lymphocytes is associated with mucosal damage in SIV infection.
Klatt NR, Estes JD, Sun X, Ortiz AM, Barber JS, Harris LD, Cervasi B, Yokomizo LK, Pan L, Vinton CL, Tabb B, Canary LA, Dang Q, Hirsch VM, Alter G, Belkaid Y, Lifson JD, Silvestri G, Milner JD, Paiardini M, Haddad EK, Brenchley JM. Klatt NR, et al. Among authors: brenchley jm. Mucosal Immunol. 2012 Nov;5(6):646-57. doi: 10.1038/mi.2012.38. Epub 2012 May 30. Mucosal Immunol. 2012. PMID: 22643849 Free PMC article.
High production rates sustain in vivo levels of PD-1high simian immunodeficiency virus-specific CD8 T cells in the face of rapid clearance.
Petrovas C, Yamamoto T, Price DA, Rao SS, Klatt NR, Brenchley JM, Douek DC, Gostick E, Angermann BR, Grossman Z, Macallan DC, Meier-Schellersheim M, Koup RA. Petrovas C, et al. Among authors: brenchley jm. J Virol. 2013 Sep;87(17):9836-44. doi: 10.1128/JVI.01001-13. Epub 2013 Jul 3. J Virol. 2013. PMID: 23824823 Free PMC article.
Homeostatic cytokines induce CD4 downregulation in African green monkeys independently of antigen exposure to generate simian immunodeficiency virus-resistant CD8αα T cells.
Perkins MR, Briant JA, Calantone N, Whitted S, Vinton CL, Klatt NR, Ourmanov I, Ortiz AM, Hirsch VM, Brenchley JM. Perkins MR, et al. Among authors: brenchley jm. J Virol. 2014 Sep;88(18):10714-24. doi: 10.1128/JVI.01331-14. Epub 2014 Jul 2. J Virol. 2014. PMID: 24991011 Free PMC article.
196 results