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Characterization of the Pharmacokinetic and Pharmacodynamic Profile of Apraglutide, a Glucagon-Like Peptide-2 Analog, in Healthy Volunteers.
Bolognani F, Kruithof AC, Schulthess P, Machacek M, de Kam ML, Bergmann KR, van Gent M, Moerland M, Crenn P, Greig G, Gal P. Bolognani F, et al. Among authors: machacek m. J Pharmacol Exp Ther. 2023 Aug;386(2):129-137. doi: 10.1124/jpet.123.001582. Epub 2023 Jun 14. J Pharmacol Exp Ther. 2023. PMID: 37316329 Clinical Trial.
Safety and Tolerability, Pharmacokinetics, and Pharmacodynamics of ACT017, an Antiplatelet GPVI (Glycoprotein VI) Fab.
Voors-Pette C, Lebozec K, Dogterom P, Jullien L, Billiald P, Ferlan P, Renaud L, Favre-Bulle O, Avenard G, Machacek M, Plétan Y, Jandrot-Perrus M. Voors-Pette C, et al. Among authors: machacek m. Arterioscler Thromb Vasc Biol. 2019 May;39(5):956-964. doi: 10.1161/ATVBAHA.118.312314. Arterioscler Thromb Vasc Biol. 2019. PMID: 31017822 Free article. Clinical Trial.
First-in-man dose escalation and pharmacokinetic study of CAP7.1, a novel prodrug of etoposide, in adults with refractory solid tumours.
Keilholz U, Rohde L, Mehlitz P, Knoedler M, Schmittel A, Kümmerlen V, Klinghammer K, Treasure P, Lassus M, Steventon G, Machacek M, Utku N. Keilholz U, et al. Among authors: machacek m. Eur J Cancer. 2017 Jul;80:14-25. doi: 10.1016/j.ejca.2017.03.032. Epub 2017 May 19. Eur J Cancer. 2017. PMID: 28531881 Clinical Trial.
Fabrication and characterization of new levan@CBD biocomposite sponges as potential materials in natural, non-toxic wound dressing applications.
Chelminiak-Dudkiewicz D, Machacek M, Dlugaszewska J, Wujak M, Smolarkiewicz-Wyczachowski A, Bocian S, Mylkie K, Goslinski T, Marszall MP, Ziegler-Borowska M. Chelminiak-Dudkiewicz D, et al. Among authors: machacek m. Int J Biol Macromol. 2023 Dec 31;253(Pt 3):126933. doi: 10.1016/j.ijbiomac.2023.126933. Epub 2023 Sep 16. Int J Biol Macromol. 2023. PMID: 37722631 Free article.
113 results