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Functional LTCC-β2AR Complex Needs Caveolin-3 and Is Disrupted in Heart Failure.
Sanchez-Alonso JL, Fedele L, Copier JS, Lucarelli C, Mansfield C, Judina A, Houser SR, Brand T, Gorelik J. Sanchez-Alonso JL, et al. Among authors: mansfield c. Circ Res. 2023 Jul 7;133(2):120-137. doi: 10.1161/CIRCRESAHA.123.322508. Epub 2023 Jun 14. Circ Res. 2023. PMID: 37313722 Free PMC article.
High levels of circulating epinephrine trigger apical cardiodepression in a β2-adrenergic receptor/Gi-dependent manner: a new model of Takotsubo cardiomyopathy.
Paur H, Wright PT, Sikkel MB, Tranter MH, Mansfield C, O'Gara P, Stuckey DJ, Nikolaev VO, Diakonov I, Pannell L, Gong H, Sun H, Peters NS, Petrou M, Zheng Z, Gorelik J, Lyon AR, Harding SE. Paur H, et al. Among authors: mansfield c. Circulation. 2012 Aug 7;126(6):697-706. doi: 10.1161/CIRCULATIONAHA.112.111591. Epub 2012 Jun 25. Circulation. 2012. PMID: 22732314 Free PMC article.
Microdomain-Specific Modulation of L-Type Calcium Channels Leads to Triggered Ventricular Arrhythmia in Heart Failure.
Sanchez-Alonso JL, Bhargava A, O'Hara T, Glukhov AV, Schobesberger S, Bhogal N, Sikkel MB, Mansfield C, Korchev YE, Lyon AR, Punjabi PP, Nikolaev VO, Trayanova NA, Gorelik J. Sanchez-Alonso JL, et al. Among authors: mansfield c. Circ Res. 2016 Sep 30;119(8):944-55. doi: 10.1161/CIRCRESAHA.116.308698. Epub 2016 Aug 29. Circ Res. 2016. PMID: 27572487 Free PMC article.
T-tubule remodelling disturbs localized β2-adrenergic signalling in rat ventricular myocytes during the progression of heart failure.
Schobesberger S, Wright P, Tokar S, Bhargava A, Mansfield C, Glukhov AV, Poulet C, Buzuk A, Monszpart A, Sikkel M, Harding SE, Nikolaev VO, Lyon AR, Gorelik J. Schobesberger S, et al. Among authors: mansfield c. Cardiovasc Res. 2017 Jun 1;113(7):770-782. doi: 10.1093/cvr/cvx074. Cardiovasc Res. 2017. PMID: 28505272 Free PMC article.
Mediastinal Lymphadenopathy, Class-Switched Auto-Antibodies and Myocardial Immune-Complexes During Heart Failure in Rodents and Humans.
Sintou A, Mansfield C, Iacob A, Chowdhury RA, Narodden S, Rothery SM, Podovei R, Sanchez-Alonso JL, Ferraro E, Swiatlowska P, Harding SE, Prasad S, Rosenthal N, Gorelik J, Sattler S. Sintou A, et al. Among authors: mansfield c. Front Cell Dev Biol. 2020 Aug 7;8:695. doi: 10.3389/fcell.2020.00695. eCollection 2020. Front Cell Dev Biol. 2020. PMID: 32850816 Free PMC article.
Local hyperactivation of L-type Ca2+ channels increases spontaneous Ca2+ release activity and cellular hypertrophy in right ventricular myocytes from heart failure rats.
Medvedev RY, Sanchez-Alonso JL, Mansfield CA, Judina A, Francis AJ, Pagiatakis C, Trayanova N, Glukhov AV, Miragoli M, Faggian G, Gorelik J. Medvedev RY, et al. Among authors: mansfield ca. Sci Rep. 2021 Mar 1;11(1):4840. doi: 10.1038/s41598-021-84275-w. Sci Rep. 2021. PMID: 33649357 Free PMC article.
460 results