Wright GD - Search Results

1

Isomerization of bioactive acylhydrazones triggered by light or thiols.

Zhang Z, Le GNT, Ge Y, Tang X, Chen X, Ejim L, Bordeleau E, Wright GD, Burns DC, Tran S, Axerio-Cilies P, Wang YT, Dong M, Woolley GA. Zhang Z, et al. Among authors: wright gd. Nat Chem. 2023 Sep;15(9):1285-1295. doi: 10.1038/s41557-023-01239-5. Epub 2023 Jun 12. Nat Chem. 2023. PMID: 37308709

2

Homoserine dehydrogenase from Saccharomyces cerevisiae: kinetic mechanism and stereochemistry of hydride transfer.

Jacques SL, Ejim LJ, Wright GD. Jacques SL, et al. Among authors: wright gd. Biochim Biophys Acta. 2001 Jan 12;1544(1-2):42-54. doi: 10.1016/s0167-4838(00)00202-8. Biochim Biophys Acta. 2001. PMID: 11341915

3

Enzyme-assisted suicide: molecular basis for the antifungal activity of 5-hydroxy-4-oxonorvaline by potent inhibition of homoserine dehydrogenase.

Jacques SL, Mirza IA, Ejim L, Koteva K, Hughes DW, Green K, Kinach R, Honek JF, Lai HK, Berghuis AM, Wright GD. Jacques SL, et al. Among authors: wright gd. Chem Biol. 2003 Oct;10(10):989-95. doi: 10.1016/j.chembiol.2003.09.015. Chem Biol. 2003. PMID: 14583265

4

Cystathionine beta-lyase is important for virulence of Salmonella enterica serovar Typhimurium.

Ejim LJ, D'Costa VM, Elowe NH, Loredo-Osti JC, Malo D, Wright GD. Ejim LJ, et al. Among authors: wright gd. Infect Immun. 2004 Jun;72(6):3310-4. doi: 10.1128/IAI.72.6.3310-3314.2004. Infect Immun. 2004. PMID: 15155634 Free PMC article.

5

New phenolic inhibitors of yeast homoserine dehydrogenase.

Ejim L, Mirza IA, Capone C, Nazi I, Jenkins S, Chee GL, Berghuis AM, Wright GD. Ejim L, et al. Among authors: wright gd. Bioorg Med Chem. 2004 Jul 15;12(14):3825-30. doi: 10.1016/j.bmc.2004.05.009. Bioorg Med Chem. 2004. PMID: 15210149

6

Inhibitors of bacterial cystathionine beta-lyase: leads for new antimicrobial agents and probes of enzyme structure and function.

Ejim LJ, Blanchard JE, Koteva KP, Sumerfield R, Elowe NH, Chechetto JD, Brown ED, Junop MS, Wright GD. Ejim LJ, et al. Among authors: wright gd. J Med Chem. 2007 Feb 22;50(4):755-64. doi: 10.1021/jm061132r. J Med Chem. 2007. PMID: 17300162

7

Rifamycin antibiotic resistance by ADP-ribosylation: Structure and diversity of Arr.

Baysarowich J, Koteva K, Hughes DW, Ejim L, Griffiths E, Zhang K, Junop M, Wright GD. Baysarowich J, et al. Among authors: wright gd. Proc Natl Acad Sci U S A. 2008 Mar 25;105(12):4886-91. doi: 10.1073/pnas.0711939105. Epub 2008 Mar 18. Proc Natl Acad Sci U S A. 2008. PMID: 18349144 Free PMC article.

8

Isolation of flavonoids from the heartwood and resin of Prunus avium and some preliminary biological investigations.

McNulty J, Nair JJ, Bollareddy E, Keskar K, Thorat A, Crankshaw DJ, Holloway AC, Khan G, Wright GD, Ejim L. McNulty J, et al. Among authors: wright gd. Phytochemistry. 2009 Dec;70(17-18):2040-6. doi: 10.1016/j.phytochem.2009.08.018. Phytochemistry. 2009. PMID: 19837443

9

Combinations of antibiotics and nonantibiotic drugs enhance antimicrobial efficacy.

Ejim L, Farha MA, Falconer SB, Wildenhain J, Coombes BK, Tyers M, Brown ED, Wright GD. Ejim L, et al. Among authors: wright gd. Nat Chem Biol. 2011 Jun;7(6):348-50. doi: 10.1038/nchembio.559. Epub 2011 Apr 24. Nat Chem Biol. 2011. PMID: 21516114

10

A small molecule discrimination map of the antibiotic resistance kinome.

Shakya T, Stogios PJ, Waglechner N, Evdokimova E, Ejim L, Blanchard JE, McArthur AG, Savchenko A, Wright GD. Shakya T, et al. Among authors: wright gd. Chem Biol. 2011 Dec 23;18(12):1591-601. doi: 10.1016/j.chembiol.2011.10.018. Chem Biol. 2011. PMID: 22195561

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