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Single cell and spatial sequencing define processes by which keratinocytes and fibroblasts amplify inflammatory responses in psoriasis.
Ma F, Plazyo O, Billi AC, Tsoi LC, Xing X, Wasikowski R, Gharaee-Kermani M, Hile G, Jiang Y, Harms PW, Xing E, Kirma J, Xi J, Hsu JE, Sarkar MK, Chung Y, Di Domizio J, Gilliet M, Ward NL, Maverakis E, Klechevsky E, Voorhees JJ, Elder JT, Lee JH, Kahlenberg JM, Pellegrini M, Modlin RL, Gudjonsson JE. Ma F, et al. Among authors: pellegrini m. Nat Commun. 2023 Jun 12;14(1):3455. doi: 10.1038/s41467-023-39020-4. Nat Commun. 2023. PMID: 37308489 Free PMC article.
Propionibacterium acnes bacteriophages display limited genetic diversity and broad killing activity against bacterial skin isolates.
Marinelli LJ, Fitz-Gibbon S, Hayes C, Bowman C, Inkeles M, Loncaric A, Russell DA, Jacobs-Sera D, Cokus S, Pellegrini M, Kim J, Miller JF, Hatfull GF, Modlin RL. Marinelli LJ, et al. Among authors: pellegrini m. mBio. 2012 Sep 25;3(5):e00279-12. doi: 10.1128/mBio.00279-12. Print 2012. mBio. 2012. PMID: 23015740 Free PMC article.
IL-32 is a molecular marker of a host defense network in human tuberculosis.
Montoya D, Inkeles MS, Liu PT, Realegeno S, Teles RM, Vaidya P, Munoz MA, Schenk M, Swindell WR, Chun R, Zavala K, Hewison M, Adams JS, Horvath S, Pellegrini M, Bloom BR, Modlin RL. Montoya D, et al. Among authors: pellegrini m. Sci Transl Med. 2014 Aug 20;6(250):250ra114. doi: 10.1126/scitranslmed.3009546. Sci Transl Med. 2014. PMID: 25143364 Free PMC article.
Imatinib Triggers Phagolysosome Acidification and Antimicrobial Activity against Mycobacterium bovis Bacille Calmette-Guérin in Glucocorticoid-Treated Human Macrophages.
Steiger J, Stephan A, Inkeles MS, Realegeno S, Bruns H, Kröll P, de Castro Kroner J, Sommer A, Batinica M, Pitzler L, Kalscheuer R, Hartmann P, Plum G, Stenger S, Pellegrini M, Brachvogel B, Modlin RL, Fabri M. Steiger J, et al. Among authors: pellegrini m. J Immunol. 2016 Jul 1;197(1):222-32. doi: 10.4049/jimmunol.1502407. Epub 2016 May 27. J Immunol. 2016. PMID: 27233968 Free PMC article.
S100A12 Is Part of the Antimicrobial Network against Mycobacterium leprae in Human Macrophages.
Realegeno S, Kelly-Scumpia KM, Dang AT, Lu J, Teles R, Liu PT, Schenk M, Lee EY, Schmidt NW, Wong GC, Sarno EN, Rea TH, Ochoa MT, Pellegrini M, Modlin RL. Realegeno S, et al. Among authors: pellegrini m. PLoS Pathog. 2016 Jun 29;12(6):e1005705. doi: 10.1371/journal.ppat.1005705. eCollection 2016 Jun. PLoS Pathog. 2016. PMID: 27355424 Free PMC article.
Cutaneous wound healing through paradoxical MAPK activation by BRAF inhibitors.
Escuin-Ordinas H, Li S, Xie MW, Sun L, Hugo W, Huang RR, Jiao J, de-Faria FM, Realegeno S, Krystofinski P, Azhdam A, Komenan SM, Atefi M, Comin-Anduix B, Pellegrini M, Cochran AJ, Modlin RL, Herschman HR, Lo RS, McBride WH, Segura T, Ribas A. Escuin-Ordinas H, et al. Among authors: pellegrini m. Nat Commun. 2016 Aug 1;7:12348. doi: 10.1038/ncomms12348. Nat Commun. 2016. PMID: 27476449 Free PMC article.
Cell-type deconvolution with immune pathways identifies gene networks of host defense and immunopathology in leprosy.
Inkeles MS, Teles RM, Pouldar D, Andrade PR, Madigan CA, Lopez D, Ambrose M, Noursadeghi M, Sarno EN, Rea TH, Ochoa MT, Iruela-Arispe ML, Swindell WR, Ottenhoff TH, Geluk A, Bloom BR, Pellegrini M, Modlin RL. Inkeles MS, et al. Among authors: pellegrini m. JCI Insight. 2016 Sep 22;1(15):e88843. doi: 10.1172/jci.insight.88843. JCI Insight. 2016. PMID: 27699251 Free PMC article.
Mycobacterium tuberculosis Transfer RNA Induces IL-12p70 via Synergistic Activation of Pattern Recognition Receptors within a Cell Network.
Keegan C, Krutzik S, Schenk M, Scumpia PO, Lu J, Pang YLJ, Russell BS, Lim KS, Shell S, Prestwich E, Su D, Elashoff D, Hershberg RM, Bloom BR, Belisle JT, Fortune S, Dedon PC, Pellegrini M, Modlin RL. Keegan C, et al. Among authors: pellegrini m. J Immunol. 2018 May 1;200(9):3244-3258. doi: 10.4049/jimmunol.1701733. Epub 2018 Apr 2. J Immunol. 2018. PMID: 29610140 Free PMC article.
1,669 results