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In vitro activity, ultrastructural analysis and in silico pharmacokinetic properties (ADMET) of thiazole compounds against adult worms of Schistosoma mansoni.
Silva DVSPD, Nascimento PHDB, Rocha JVRD, Marques DSC, Brayner FA, Alves LC, Araújo HDA, Cruz Filho IJD, Albuquerque MCPA, Lima MDCA, Aires AL. Silva DVSPD, et al. Among authors: cruz filho ijd. Acta Trop. 2023 Sep;245:106965. doi: 10.1016/j.actatropica.2023.106965. Epub 2023 Jun 7. Acta Trop. 2023. PMID: 37295486
Plumbagin: A Promising In Vivo Antiparasitic Candidate against Schistosoma mansoni and In Silico Pharmacokinetic Properties (ADMET).
Silva LMN, França WWM, Santos VHB, Souza RAF, Silva AM, Diniz EGM, Aguiar TWA, Rocha JVR, Souza MAA, Nascimento WRC, Lima Neto RG, Cruz Filho IJ, Ximenes ECPA, Araújo HDA, Aires AL, Albuquerque MCPA. Silva LMN, et al. Biomedicines. 2023 Aug 22;11(9):2340. doi: 10.3390/biomedicines11092340. Biomedicines. 2023. PMID: 37760782 Free PMC article.
In silico ADMET prediction, evaluation of cytotoxicity in mouse splenocytes and preliminary evaluation of in vitro antimalarial activity of 4-(4-chlorophenyl)thiazole compounds.
Silva BRMGD, Bezerra Júnior NDS, Oliveira JF, Duarte DMFA, Marques DSC, Nogueira F, Lima MCA, Cruz Filho IJD. Silva BRMGD, et al. Among authors: cruz filho ijd. An Acad Bras Cienc. 2023 Dec 4;95(suppl 2):e20230566. doi: 10.1590/0001-3765202320230566. eCollection 2023. An Acad Bras Cienc. 2023. PMID: 38055446 Free article.
Saline extract from Malpighia emarginata DC leaves showed higher polyphenol presence, antioxidant and antifungal activity and promoted cell proliferation in mice splenocytes.
Barros BRS, Barboza BR, Ramos BA, Moura MC, Coelho LCBB, Napoleão TH, Correia MTS, Paiva PMG, Cruz Filho IJD, Silva TDD, Lima CSA, Melo CML. Barros BRS, et al. Among authors: cruz filho ijd. An Acad Bras Cienc. 2019;91(1):e20190916. doi: 10.1590/0001-3765201920180358. Epub 2019 Apr 8. An Acad Bras Cienc. 2019. PMID: 30994765 Free article.