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A randomized clinical trial of on-demand oral pre-exposure prophylaxis does not modulate lymphoid/myeloid HIV target cell density in the foreskin.
Rametse CL, Webb EL, Herrera C, Alinde B, Besethi A, Motaung B, Mbangiwa T, Leach L, Sebaa S, Pillay AAP, Seiphetlo TB, Malhangu B, Petkov S, Else L, Mugaba S, Namubiru P, Odoch G, Opoka D, Serwanga J, Ssemata AS, Kaleebu P, Khoo S, Lebina L, Martinson N, Chiodi F, Fox J, Gray CM; CHAPS consortium. Rametse CL, et al. Among authors: fox j. AIDS. 2023 Sep 1;37(11):1651-1659. doi: 10.1097/QAD.0000000000003619. Epub 2023 Jun 6. AIDS. 2023. PMID: 37289572 Clinical Trial.
Short-term oral pre-exposure prophylaxis against HIV-1 modulates the transcriptome of foreskin tissue in young men in Africa.
Petkov S, Herrera C, Else L, Lebina L, Opoka D, Seiphetlo TB, Pillay AA, Mugaba S, Namubiru P, Odoch G, Ssemata AS, Serwanga J, Kaleebu P, Webb EL, Khoo S, Martinson N, Gray CM, Fox J, Chiodi F. Petkov S, et al. Among authors: fox j. Front Immunol. 2022 Nov 18;13:1009978. doi: 10.3389/fimmu.2022.1009978. eCollection 2022. Front Immunol. 2022. PMID: 36479111 Free PMC article. Clinical Trial.
Optimisation and Validation of a conventional ELISA and cut-offs for detecting and quantifying anti-SARS-CoV-2 Spike, RBD, and Nucleoprotein IgG, IgM, and IgA antibodies in Uganda.
Oluka GK, Namubiru P, Kato L, Ankunda V, Gombe B, Cotten M; COVID-19 Immunoprofiling Team; Musenero M, Kaleebu P, Fox J, Serwanga J. Oluka GK, et al. Among authors: fox j. Front Immunol. 2023 Mar 14;14:1113194. doi: 10.3389/fimmu.2023.1113194. eCollection 2023. Front Immunol. 2023. PMID: 36999017 Free PMC article.
Rapid, early, and potent Spike-directed IgG, IgM, and IgA distinguish asymptomatic from mildly symptomatic COVID-19 in Uganda, with IgG persisting for 28 months.
Serwanga J, Ankunda V, Sembera J, Kato L, Oluka GK, Baine C, Odoch G, Kayiwa J, Auma BO, Jjuuko M, Nsereko C, Cotten M, Onyachi N, Muwanga M, Lutalo T, Fox J, Musenero M, Kaleebu P; COVID-19 Immunoprofiling Team. Serwanga J, et al. Among authors: fox j. Front Immunol. 2023 Mar 16;14:1152522. doi: 10.3389/fimmu.2023.1152522. eCollection 2023. Front Immunol. 2023. PMID: 37006272 Free PMC article.
Dose finding study for on-demand HIV pre-exposure prophylaxis for insertive sex in sub-Saharan Africa: results from the CHAPS open label randomised controlled trial.
Herrera C, Serwanga J, Else L, Limakatso L, Opoka D, Ssemata AS, Pillay AD, Namubiru P, Seiphetlo TB, Odoch G, Mugaba S, Seatlholo P, Alieu A, Penchala SD, Muhumuza R, Alinde B, Petkov S, O'Hagan K, Callebaut C, Seeley J, Weiss H, Khoo S, Chiodi F, Gray CM, Kaleebu P, Webb EL, Martinson N, Fox J; CHAPS. Herrera C, et al. Among authors: fox j. EBioMedicine. 2023 Jul;93:104648. doi: 10.1016/j.ebiom.2023.104648. Epub 2023 Jun 14. EBioMedicine. 2023. PMID: 37327677 Free PMC article. Clinical Trial.
A qualitative study to explore daily versus on-demand oral pre-exposure prophylaxis (PrEP) in young people from South Africa, Uganda and Zimbabwe.
Dietrich JJ, Ahmed N, Tshabalala G, Wu M, Mulaudzi M, Hornschuh S, Atujuna M, Muhumuza R, Ssemata AS, Stranix-Chibanda L, Nematadzira T, Bekker LG, Martinson N, Seeley J, Fox J. Dietrich JJ, et al. Among authors: fox j. PLoS One. 2023 Jun 29;18(6):e0287627. doi: 10.1371/journal.pone.0287627. eCollection 2023. PLoS One. 2023. PMID: 37384792 Free PMC article.
Evaluation of a human mucosal tissue explant model for SARS-CoV-2 replication.
Gordhan BG, Herrera C, Pillay AD, Seiphetlo T, Ealand CS, Machowski E, Singh N, Seatholo N, Otwombe K, Lebina L, Frise R, Scarlatti G, Chiodi F, Martinson N, Fox J, Kana BD. Gordhan BG, et al. Among authors: fox j. PLoS One. 2023 Sep 28;18(9):e0291146. doi: 10.1371/journal.pone.0291146. eCollection 2023. PLoS One. 2023. PMID: 37769001 Free PMC article.
Preferences for oral PrEP dosing among adolescent boys and young men in three sub-Saharan African countries.
Kakande A, Ssemata AS, Muhumuza R, Atujuna M, Abaasa A, Ndekezi D, Tshabalala G, Nematadzira T, Hornschuh S, Nomvuyo M, Ahmed N, Maluadzi M, Anne Weiss H, Webb E, Stranix-Chibanda L, Janine Dietrich J, Seeley J, Fox J. Kakande A, et al. Among authors: fox j. PLoS One. 2023 Oct 9;18(10):e0285132. doi: 10.1371/journal.pone.0285132. eCollection 2023. PLoS One. 2023. PMID: 37812644 Free PMC article.
Ex vivo challenge models for infectious diseases.
Gordhan BG, Liebenberg D, Scarlatti G, Herrera C, Chiodi F, Martinson N, Fox J, Kana BD. Gordhan BG, et al. Among authors: fox j. Crit Rev Microbiol. 2023 Nov 1:1-20. doi: 10.1080/1040841X.2023.2274855. Online ahead of print. Crit Rev Microbiol. 2023. PMID: 37909097 Review.
Bacterial microbiome and host inflammatory gene expression in foreskin tissue.
Maust BS, Petkov S, Herrera C, Feng C, Brown BP, Lebina L, Opoka D, Ssemata A, Pillay N, Serwanga J, Seatlholo P, Namubiru P, Odoch G, Mugaba S, Seiphetlo T, Gray CM, Kaleebu P, Webb EL, Martinson N, Chiodi F, Fox J, Jaspan HB; CHAPS team. Maust BS, et al. Among authors: fox j. Heliyon. 2023 Nov 14;9(11):e22145. doi: 10.1016/j.heliyon.2023.e22145. eCollection 2023 Nov. Heliyon. 2023. PMID: 38053902 Free PMC article.
5,676 results