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2,767 results

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Class B1 GPCR activation by an intracellular agonist.
Kobayashi K, Kawakami K, Kusakizako T, Tomita A, Nishimura M, Sawada K, Okamoto HH, Hiratsuka S, Nakamura G, Kuwabara R, Noda H, Muramatsu H, Shimizu M, Taguchi T, Inoue A, Murata T, Nureki O. Kobayashi K, et al. Among authors: murata t. Nature. 2023 Jun;618(7967):1085-1093. doi: 10.1038/s41586-023-06169-3. Epub 2023 Jun 7. Nature. 2023. PMID: 37286611 Free PMC article.
Mitochondrial sorting and assembly machinery operates by β-barrel switching.
Takeda H, Tsutsumi A, Nishizawa T, Lindau C, Busto JV, Wenz LS, Ellenrieder L, Imai K, Straub SP, Mossmann W, Qiu J, Yamamori Y, Tomii K, Suzuki J, Murata T, Ogasawara S, Nureki O, Becker T, Pfanner N, Wiedemann N, Kikkawa M, Endo T. Takeda H, et al. Among authors: murata t. Nature. 2021 Feb;590(7844):163-169. doi: 10.1038/s41586-020-03113-7. Epub 2021 Jan 6. Nature. 2021. PMID: 33408415
G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody.
Hino T, Arakawa T, Iwanari H, Yurugi-Kobayashi T, Ikeda-Suno C, Nakada-Nakura Y, Kusano-Arai O, Weyand S, Shimamura T, Nomura N, Cameron AD, Kobayashi T, Hamakubo T, Iwata S, Murata T. Hino T, et al. Among authors: murata t. Nature. 2012 Jan 29;482(7384):237-40. doi: 10.1038/nature10750. Nature. 2012. PMID: 22286059 Free PMC article.
Crystal structures of the human adiponectin receptors.
Tanabe H, Fujii Y, Okada-Iwabu M, Iwabu M, Nakamura Y, Hosaka T, Motoyama K, Ikeda M, Wakiyama M, Terada T, Ohsawa N, Hato M, Ogasawara S, Hino T, Murata T, Iwata S, Hirata K, Kawano Y, Yamamoto M, Kimura-Someya T, Shirouzu M, Yamauchi T, Kadowaki T, Yokoyama S. Tanabe H, et al. Among authors: murata t. Nature. 2015 Apr 16;520(7547):312-316. doi: 10.1038/nature14301. Epub 2015 Apr 8. Nature. 2015. PMID: 25855295 Free PMC article.
Structural insights into the subtype-selective antagonist binding to the M2 muscarinic receptor.
Suno R, Lee S, Maeda S, Yasuda S, Yamashita K, Hirata K, Horita S, Tawaramoto MS, Tsujimoto H, Murata T, Kinoshita M, Yamamoto M, Kobilka BK, Vaidehi N, Iwata S, Kobayashi T. Suno R, et al. Among authors: murata t. Nat Chem Biol. 2018 Dec;14(12):1150-1158. doi: 10.1038/s41589-018-0152-y. Epub 2018 Nov 12. Nat Chem Biol. 2018. PMID: 30420692 Free PMC article.
Ligand binding to human prostaglandin E receptor EP4 at the lipid-bilayer interface.
Toyoda Y, Morimoto K, Suno R, Horita S, Yamashita K, Hirata K, Sekiguchi Y, Yasuda S, Shiroishi M, Shimizu T, Urushibata Y, Kajiwara Y, Inazumi T, Hotta Y, Asada H, Nakane T, Shiimura Y, Nakagita T, Tsuge K, Yoshida S, Kuribara T, Hosoya T, Sugimoto Y, Nomura N, Sato M, Hirokawa T, Kinoshita M, Murata T, Takayama K, Yamamoto M, Narumiya S, Iwata S, Kobayashi T. Toyoda Y, et al. Among authors: murata t. Nat Chem Biol. 2019 Jan;15(1):18-26. doi: 10.1038/s41589-018-0131-3. Epub 2018 Dec 3. Nat Chem Biol. 2019. PMID: 30510193
Identifying antibiotics based on structural differences in the conserved allostery from mitochondrial heme-copper oxidases.
Nishida Y, Yanagisawa S, Morita R, Shigematsu H, Shinzawa-Itoh K, Yuki H, Ogasawara S, Shimuta K, Iwamoto T, Nakabayashi C, Matsumura W, Kato H, Gopalasingam C, Nagao T, Qaqorh T, Takahashi Y, Yamazaki S, Kamiya K, Harada R, Mizuno N, Takahashi H, Akeda Y, Ohnishi M, Ishii Y, Kumasaka T, Murata T, Muramoto K, Tosha T, Shiro Y, Honma T, Shigeta Y, Kubo M, Takashima S, Shintani Y. Nishida Y, et al. Among authors: murata t. Nat Commun. 2022 Dec 8;13(1):7591. doi: 10.1038/s41467-022-34771-y. Nat Commun. 2022. PMID: 36481732 Free PMC article.
2,767 results