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The novel uncompetitive NMDA receptor antagonist esmethadone (REL-1017) has no meaningful abuse potential in recreational drug users.
Transl Psychiatry. 2023 Jun 7;13(1):192. doi: 10.1038/s41398-023-02473-8.
Transl Psychiatry. 2023.
PMID: 37286536
Free PMC article.
Clinical Trial.
The role of abuse liability testing in drug control procedures.
McClain H Jr, Sapienza F.
McClain H Jr, et al.
NIDA Res Monogr. 1989;92:21-42.
NIDA Res Monogr. 1989.
PMID: 2512493
No abstract available.
Item in Clipboard
Psychedelic drug abuse potential assessment research for new drug applications and Controlled Substances Act scheduling.
Henningfield JE, Coe MA, Griffiths RR, Belouin SJ, Berger A, Coker AR, Comer SD, Heal DJ, Hendricks PS, Nichols CD, Sapienza F, Vocci FJ, Zia FZ.
Henningfield JE, et al.
Neuropharmacology. 2022 Nov 1;218:109220. doi: 10.1016/j.neuropharm.2022.109220. Epub 2022 Aug 17.
Neuropharmacology. 2022.
PMID: 35987353
Free article.
Review.
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Letter to the Editor regarding 'Unique pharmacodynamic properties and low abuse liability of the µ-opioid receptor ligand (S)-methadone'.
Pappagallo M, Kosten TR, Gorodetzky CW, Vocci FJ, Sapienza FL, De Martin S, Comai S, Mattarei A, Inturrisi CE, Manfredi PL.
Pappagallo M, et al. Among authors: sapienza fl.
Mol Psychiatry. 2024 May 28. doi: 10.1038/s41380-024-02621-6. Online ahead of print.
Mol Psychiatry. 2024.
PMID: 38806691
No abstract available.
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Abuse deterrent formulations and the Controlled Substances Act (CSA).
Sapienza FL.
Sapienza FL.
Drug Alcohol Depend. 2006 Jun;83 Suppl 1:S23-30. doi: 10.1016/j.drugalcdep.2005.11.028. Epub 2006 Mar 9.
Drug Alcohol Depend. 2006.
PMID: 16529882
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