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The novel uncompetitive NMDA receptor antagonist esmethadone (REL-1017) has no meaningful abuse potential in recreational drug users.
Shram MJ, Henningfield JE, Apseloff G, Gorodetzky CW, De Martin S, Vocci FL, Sapienza FL, Kosten TR, Huston J, Buchhalter A, Ashworth J, Lanier R, Folli F, Mattarei A, Guidetti C, Comai S, O'Gorman C, Traversa S, Inturrisi CE, Manfredi PL, Pappagallo M. Shram MJ, et al. Among authors: comai s. Transl Psychiatry. 2023 Jun 7;13(1):192. doi: 10.1038/s41398-023-02473-8. Transl Psychiatry. 2023. PMID: 37286536 Free PMC article. Clinical Trial.
Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E.
Aguilar-Valles A, Haji N, De Gregorio D, Matta-Camacho E, Eslamizade MJ, Popic J, Sharma V, Cao R, Rummel C, Tanti A, Wiebe S, Nuñez N, Comai S, Nadon R, Luheshi G, Mechawar N, Turecki G, Lacaille JC, Gobbi G, Sonenberg N. Aguilar-Valles A, et al. Among authors: comai s. Nat Commun. 2018 Jun 25;9(1):2459. doi: 10.1038/s41467-018-04883-5. Nat Commun. 2018. PMID: 29941989 Free PMC article.
Effects of repeated lysergic acid diethylamide (LSD) on the mouse brain endocannabinoidome and gut microbiome.
Inserra A, Giorgini G, Lacroix S, Bertazzo A, Choo J, Markopolous A, Grant E, Abolghasemi A, De Gregorio D, Flamand N, Rogers G, Comai S, Silvestri C, Gobbi G, Di Marzo V. Inserra A, et al. Among authors: comai s. Br J Pharmacol. 2023 Mar;180(6):721-739. doi: 10.1111/bph.15977. Epub 2022 Dec 12. Br J Pharmacol. 2023. PMID: 36316276 Free article.
Search for melanoma markers in plasma and serum samples.
Seraglia R, Vogliardi S, Allegri G, Comai S, Lise M, Rossi CR, Mocellin S, Scalerta R, Ragazzi E, Traldi P. Seraglia R, et al. Among authors: comai s. Eur J Mass Spectrom (Chichester). 2005;11(3):353-60. doi: 10.1255/ejms.751. Eur J Mass Spectrom (Chichester). 2005. PMID: 16107750
105 results