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Page 1
Macrophage-Mediated Antibody Dependent Effector Function in Aggressive B-Cell Lymphoma Treatment is Enhanced by Ibrutinib via Inhibition of JAK2.
Barbarino V, Henschke S, Blakemore SJ, Izquierdo E, Michalik M, Nickel N, Möllenkotte I, Vorholt D, Müller L, Brinker R, Fedorchenko O, Mikhael N, Seeger-Nukpezah T, Hallek M, Pallasch CP. Barbarino V, et al. Among authors: blakemore sj. Cancers (Basel). 2020 Aug 15;12(8):2303. doi: 10.3390/cancers12082303. Cancers (Basel). 2020. PMID: 32824276 Free PMC article.
Extracellular vesicles and PD-L1 suppress macrophages, inducing therapy resistance in TP53-deficient B-cell malignancies.
Izquierdo E, Vorholt D, Blakemore S, Sackey B, Nolte JL, Barbarino V, Schmitz J, Nickel N, Bachurski D, Lobastova L, Nikolic M, Michalik M, Brinker R, Merkel O, Franitza M, Georgomanolis T, Neuhaus R, Koch M, Nasada N, Knittel G, Chapuy B, Ludwig N, Meese E, Frenzel L, Reinhardt HC, Peifer M, Rebollido-Rios R, Bruns H, Krüger M, Hallek M, Pallasch CP. Izquierdo E, et al. Blood. 2022 Jun 23;139(25):3617-3629. doi: 10.1182/blood.2021014007. Blood. 2022. PMID: 35344582 Free article.
Kinase activity profiling reveals contribution of G-protein signaling modulator 2 deficiency to impaired regulatory T cell migration in rheumatoid arthritis.
Meyer A, Yan S, Golumba-Nagy V, Esser RL, Barbarino V, Blakemore SJ, Rusyn L, Nikiforov A, Seeger-Nukpezah T, Grüll H, Pallasch CP, Kofler DM. Meyer A, et al. Among authors: blakemore sj. J Autoimmun. 2021 Nov;124:102726. doi: 10.1016/j.jaut.2021.102726. Epub 2021 Sep 21. J Autoimmun. 2021. PMID: 34555678 Free article.
The proto-oncogene TCL1A deregulates cell cycle and genomic stability in CLL.
Stachelscheid J, Jiang Q, Aszyk C, Warner K, Bley N, Müller T, Vydzhak O, Symeonidis K, Crispatzu G, Mayer P, Blakemore SJ, Goehring G, Newrzela S, Hippler S, Robrecht S, Kreuzer KA, Pallasch C, Krüger M, Lechner A, Fischer K, Stilgenbauer S, Beutner D, Hallek M, Auguin D, Hüttelmaier S, Bloehdorn J, Vasyutina E, Herling M. Stachelscheid J, et al. Among authors: blakemore sj. Blood. 2023 Mar 23;141(12):1425-1441. doi: 10.1182/blood.2022015494. Blood. 2023. PMID: 36179280 Free article.
Active Akt signaling triggers CLL toward Richter transformation via overactivation of Notch1.
Kohlhaas V, Blakemore SJ, Al-Maarri M, Nickel N, Pal M, Roth A, Hövelmeyer N, Schäfer SC, Knittel G, Lohneis P, Nikolic M, Wiederstein JL, Franitza M, Georgomonolis T, Reinart N, Herling M, Herling C, Hartmann EM, Rosenwald A, Klapper W, Büttner R, Moia R, Rossi D, Boldorini R, Gaidano G, Frenzel LP, Reinhardt HC, Brüning JC, Hallek M, Krüger M, Peifer M, Pallasch CP, Wunderlich FT. Kohlhaas V, et al. Among authors: blakemore sj. Blood. 2021 Feb 4;137(5):646-660. doi: 10.1182/blood.2020005734. Blood. 2021. PMID: 33538798 Free article.
[No title available]
[No authors listed] [No authors listed] PMID: 33140819
PI3Kδ inhibition elicits anti-leukemic effects through Bim-dependent apoptosis.
Carter MJ, Cox KL, Blakemore SJ, Turaj AH, Oldham RJ, Dahal LN, Tannheimer S, Forconi F, Packham G, Cragg MS. Carter MJ, et al. Among authors: blakemore sj. Leukemia. 2017 Jun;31(6):1423-1433. doi: 10.1038/leu.2016.333. Epub 2016 Nov 15. Leukemia. 2017. PMID: 27843137 Free PMC article.
Clinical significance of TP53, BIRC3, ATM and MAPK-ERK genes in chronic lymphocytic leukaemia: data from the randomised UK LRF CLL4 trial.
Blakemore SJ, Clifford R, Parker H, Antoniou P, Stec-Dziedzic E, Larrayoz M, Davis Z, Kadalyayil L, Colins A, Robbe P, Vavoulis D, Forster J, Carr L, Morilla R, Else M, Bryant D, McCarthy H, Walewska RJ, Steele AJ, Chan J, Speight G, Stankovic T, Cragg MS, Catovsky D, Oscier DG, Rose-Zerilli MJJ, Schuh A, Strefford JC. Blakemore SJ, et al. Leukemia. 2020 Jul;34(7):1760-1774. doi: 10.1038/s41375-020-0723-2. Epub 2020 Feb 3. Leukemia. 2020. PMID: 32015491 Free PMC article. Clinical Trial.
218 results