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A multi-enzyme machine polymerizes the Haemophilus influenzae type b capsule.
Cifuente JO, Schulze J, Bethe A, Di Domenico V, Litschko C, Budde I, Eidenberger L, Thiesler H, Ramón Roth I, Berger M, Claus H, D'Angelo C, Marina A, Gerardy-Schahn R, Schubert M, Guerin ME, Fiebig T. Cifuente JO, et al. Nat Chem Biol. 2023 Jul;19(7):865-877. doi: 10.1038/s41589-023-01324-3. Epub 2023 Jun 5. Nat Chem Biol. 2023. PMID: 37277468 Free PMC article.
Structural basis of glycogen metabolism in bacteria.
Cifuente JO, Comino N, Trastoy B, D'Angelo C, Guerin ME. Cifuente JO, et al. Biochem J. 2019 Jul 31;476(14):2059-2092. doi: 10.1042/BCJ20170558. Biochem J. 2019. PMID: 31366571 Review.
Dissecting the Structural and Chemical Determinants of the "Open-to-Closed" Motion in the Mannosyltransferase PimA from Mycobacteria.
Rodrigo-Unzueta A, Ghirardello M, Urresti S, Delso I, Giganti D, Anso I, Trastoy B, Comino N, Tersa M, D'Angelo C, Cifuente JO, Marina A, Liebau J, Mäler L, Chenal A, Albesa-Jové D, Merino P, Guerin ME. Rodrigo-Unzueta A, et al. Biochemistry. 2020 Aug 18;59(32):2934-2945. doi: 10.1021/acs.biochem.0c00376. Epub 2020 Aug 4. Biochemistry. 2020. PMID: 32786405
BET inhibition reforms the immune microenvironment and alleviates T cell dysfunction in chronic lymphocytic leukemia.
Smith AL, Skupa SA, Eiken AP, Reznicek TE, Schmitz E, Williams N, Moore DY, D'Angelo CR, Kallam A, Lunning MA, Bociek RG, Vose JM, Mohamed E, Mahr AR, Denton PW, Powell B, Bollag G, Rowley MJ, El-Gamal D. Smith AL, et al. Among authors: d angelo cr. JCI Insight. 2024 May 22;9(10):e177054. doi: 10.1172/jci.insight.177054. JCI Insight. 2024. PMID: 38775157 Free article.
Novel Spirocyclic Dimer, SpiD3, Targets Chronic Lymphocytic Leukemia Survival Pathways with Potent Preclinical Effects.
Eiken AP, Smith AL, Skupa SA, Schmitz E, Rana S, Singh S, Kumar S, Mallareddy JR, de Cubas AA, Krishna A, Kalluchi A, Rowley MJ, D'Angelo CR, Lunning MA, Bociek RG, Vose JM, Natarajan A, El-Gamal D. Eiken AP, et al. Among authors: d angelo cr. Cancer Res Commun. 2024 May 22;4(5):1328-1343. doi: 10.1158/2767-9764.CRC-24-0071. Cancer Res Commun. 2024. PMID: 38687198 Free PMC article.
TRF2 as novel marker of tumor response to taxane-based therapy: from mechanistic insight to clinical implication.
Iachettini S, Terrenato I, Porru M, Di Vito S, Rizzo A, D'Angelo C, Petti E, Dinami R, Maresca C, Di Benedetto A, Palange A, Mulè A, Santoro A, Palazzo A, Fuso P, Stoppacciaro A, Vici P, Filomeno L, Di Lisa FS, Arcuri T, Krasniqi E, Fabi A, Biroccio A, Zizza P. Iachettini S, et al. Among authors: d angelo c. J Exp Clin Cancer Res. 2024 Mar 9;43(1):75. doi: 10.1186/s13046-024-02998-w. J Exp Clin Cancer Res. 2024. PMID: 38459559 Free PMC article.
362 results