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Innate phase production of IFN-γ by memory and effector T cells expressing early activation marker CD69 during infection with Cryptococcus deneoformans in the lungs.
Miyahara A, Umeki A, Sato K, Nomura T, Yamamoto H, Miyasaka T, Tanno D, Matsumoto I, Zong T, Kagesawa T, Oniyama A, Kawamura K, Yuan X, Yokoyama R, Kitai Y, Kanno E, Tanno H, Hara H, Yamasaki S, Saijo S, Iwakura Y, Ishii K, Kawakami K. Miyahara A, et al. Among authors: iwakura y. Infect Immun. 2024 May 3:e0002424. doi: 10.1128/iai.00024-24. Online ahead of print. Infect Immun. 2024. PMID: 38700335
Human Dectin-1 deficiency impairs macrophage-mediated defense against phaeohyphomycosis.
Drummond RA, Desai JV, Hsu AP, Oikonomou V, Vinh DC, Acklin JA, Abers MS, Walkiewicz MA, Anzick SL, Swamydas M, Vautier S, Natarajan M, Oler AJ, Yamanaka D, Mayer-Barber KD, Iwakura Y, Bianchi D, Driscoll B, Hauck K, Kline A, Viall NS, Zerbe CS, Ferré EM, Schmitt MM, DiMaggio T, Pittaluga S, Butman JA, Zelazny AM, Shea YR, Arias CA, Ashbaugh C, Mahmood M, Temesgen Z, Theofiles AG, Nigo M, Moudgal V, Bloch KC, Kelly SG, Whitworth MS, Rao G, Whitener CJ, Mafi N, Gea-Banacloche J, Kenyon LC, Miller WR, Boggian K, Gilbert A, Sincock M, Freeman AF, Bennett JE, Hasbun R, Mikelis CM, Kwon-Chung KJ, Belkaid Y, Brown GD, Lim JK, Kuhns DB, Holland SM, Lionakis MS. Drummond RA, et al. Among authors: iwakura y. J Clin Invest. 2022 Nov 15;132(22):e159348. doi: 10.1172/JCI159348. J Clin Invest. 2022. PMID: 36377664 Free PMC article.
mTORC1 links pathology in experimental models of Still's disease and macrophage activation syndrome.
Huang Z, You X, Chen L, Du Y, Brodeur K, Jee H, Wang Q, Linder G, Darbousset R, Cunin P, Chang MH, Wactor A, Wauford BM, Todd MJC, Wei K, Li Y, Levescot A, Iwakura Y, Pascual V, Baldwin NE, Quartier P, Li T, Gianatasio MT, Hasserjian RP, Henderson LA, Sykes DB, Mellins ED, Canna SW, Charles JF, Nigrovic PA, Lee PY. Huang Z, et al. Among authors: iwakura y. Nat Commun. 2022 Nov 28;13(1):6915. doi: 10.1038/s41467-022-34480-6. Nat Commun. 2022. PMID: 36443301 Free PMC article.
The IL-17-IL-17RA axis is required to promote osteosarcoma progression in mice.
Yoshimura N, Kariya R, Shimada M, Tateyama M, Matsunaga H, Shibata Y, Tanimura S, Takata K, Arima T, Kawakami J, Maeda K, Fukuma Y, Uragami M, Ideo K, Sugimoto K, Yonemitsu R, Matsushita K, Hisanaga S, Yugami M, Uehara Y, Masuda T, Nakamura T, Tokunaga T, Karasugi T, Sueyoshi T, Sato H, Iwakura Y, Araki K, Kobayashi E, Okada S, Miyamoto T. Yoshimura N, et al. Among authors: iwakura y. Sci Rep. 2023 Dec 7;13(1):21572. doi: 10.1038/s41598-023-49016-1. Sci Rep. 2023. PMID: 38062130 Free PMC article.
788 results