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Structure-property relationships of fluorinated carboxylic acid bioisosteres.
Alle T, Joyasawal S, Oukoloff K, Long K, Owyang Z, Francisco KR, Cahard D, Huryn DM, Ballatore C. Alle T, et al. Among authors: ballatore c. Bioorg Med Chem Lett. 2023 Jul 15;91:129363. doi: 10.1016/j.bmcl.2023.129363. Epub 2023 Jun 8. Bioorg Med Chem Lett. 2023. PMID: 37295616 Free PMC article.
Targeted Reversible Covalent Modification of a Noncatalytic Lysine of the Krev Interaction Trapped 1 Protein Enables Site-Directed Screening for Protein-Protein Interaction Inhibitors.
Francisco KR, Bruystens J, Varricchio C, McCurdy S, Wu J, Lopez-Ramirez MA, Ginsberg M, Caffrey CR, Brancale A, Gingras AR, Hixon MS, Ballatore C. Francisco KR, et al. Among authors: ballatore c. ACS Pharmacol Transl Sci. 2023 Oct 9;6(11):1651-1658. doi: 10.1021/acsptsci.3c00156. eCollection 2023 Nov 10. ACS Pharmacol Transl Sci. 2023. PMID: 37974623 Free article.
A microtubule stabilizer ameliorates protein pathogenesis and neurodegeneration in mouse models of repetitive traumatic brain injury.
Zhao X, Zeng W, Xu H, Sun Z, Hu Y, Peng B, McBride JD, Duan J, Deng J, Zhang B, Kim SJ, Zoll B, Saito T, Sasaguri H, Saido TC, Ballatore C, Yao H, Wang Z, Trojanowski JQ, Brunden KR, Lee VM, He Z. Zhao X, et al. Among authors: ballatore c. Sci Transl Med. 2023 Sep 13;15(713):eabo6889. doi: 10.1126/scitranslmed.abo6889. Epub 2023 Sep 13. Sci Transl Med. 2023. PMID: 37703352 Free PMC article.
Structure-Activity Relationships, Tolerability and Efficacy of Microtubule-Active 1,2,4-Triazolo[1,5-a]pyrimidines as Potential Candidates to Treat Human African Trypanosomiasis.
Monti L, Liu LJ, Varricchio C, Lucero B, Alle T, Yang W, Bem-Shalom I, Gilson M, Brunden KR, Brancale A, Caffrey CR, Ballatore C. Monti L, et al. Among authors: ballatore c. ChemMedChem. 2023 Oct 17;18(20):e202300193. doi: 10.1002/cmdc.202300193. Epub 2023 Jul 24. ChemMedChem. 2023. PMID: 37429821
Structure-Activity Relationships, Tolerability and Efficacy of Microtubule-Active 1,2,4-Triazolo[1,5- a ]pyrimidines as Potential Candidates to Treat Human African Trypanosomiasis.
Monti L, Liu LJ, Varricchio C, Lucero B, Alle T, Yang W, Bem-Shalom I, Gilson M, Brunden KR, Brancale A, Caffrey CR, Ballatore C. Monti L, et al. Among authors: ballatore c. bioRxiv [Preprint]. 2023 Mar 11:2023.03.11.532093. doi: 10.1101/2023.03.11.532093. bioRxiv. 2023. PMID: 36945407 Free PMC article. Updated. Preprint.
Hydrogen Bonding Parameters by Rapid Colorimetric Assessment: Evaluation of Structural Components Found in Biological Ligands and Organocatalysts.
Roenfanz HF, Paniak TJ, Berlin CB, Tran V, Francisco KR, Lassalas P, Devas A, Landes O, Rosenberger A, Rotella ME, Ballatore C, Kozlowski MC. Roenfanz HF, et al. Among authors: ballatore c. Chemistry. 2023 Jul 14;29(40):e202300696. doi: 10.1002/chem.202300696. Epub 2023 May 26. Chemistry. 2023. PMID: 36917701
Microtubule-Stabilizing 1,2,4-Triazolo[1,5-a]pyrimidines as Candidate Therapeutics for Neurodegenerative Disease: Matched Molecular Pair Analyses and Computational Studies Reveal New Structure-Activity Insights.
Alle T, Varricchio C, Yao Y, Lucero B, Nzou G, Demuro S, Muench M, Vuong KD, Oukoloff K, Cornec AS, Francisco KR, Caffrey CR, Lee VM, Smith AB 3rd, Brancale A, Brunden KR, Ballatore C. Alle T, et al. Among authors: ballatore c. J Med Chem. 2023 Jan 12;66(1):435-459. doi: 10.1021/acs.jmedchem.2c01411. Epub 2022 Dec 19. J Med Chem. 2023. PMID: 36534051 Free PMC article.
79 results