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SARS-CoV-2 infection rewires host cell metabolism and is potentially susceptible to mTORC1 inhibition.
Mullen PJ, Garcia G Jr, Purkayastha A, Matulionis N, Schmid EW, Momcilovic M, Sen C, Langerman J, Ramaiah A, Shackelford DB, Damoiseaux R, French SW, Plath K, Gomperts BN, Arumugaswami V, Christofk HR. Mullen PJ, et al. Among authors: christofk hr. Nat Commun. 2021 Mar 25;12(1):1876. doi: 10.1038/s41467-021-22166-4. Nat Commun. 2021. PMID: 33767183 Free PMC article.
Metabolic decisions in development and disease-a Keystone Symposia report.
Cable J, Pourquié O, Wellen KE, Finley LWS, Aulehla A, Gould AP, Teleman A, Tu WB, Garrett WS, Miguel-Aliaga I, Perrimon N, Hooper LV, Walhout AJM, Wei W, Alexandrov T, Erez A, Ralser M, Rabinowitz JD, Hemalatha A, Gutiérrez-Pérez P, Chandel NS, Rutter J, Locasale JW, Landoni JC, Christofk H. Cable J, et al. Ann N Y Acad Sci. 2021 Dec;1506(1):55-73. doi: 10.1111/nyas.14678. Epub 2021 Aug 19. Ann N Y Acad Sci. 2021. PMID: 34414571 Review.
TGFβ superfamily signaling regulates the state of human stem cell pluripotency and capacity to create well-structured telencephalic organoids.
Watanabe M, Buth JE, Haney JR, Vishlaghi N, Turcios F, Elahi LS, Gu W, Pearson CA, Kurdian A, Baliaouri NV, Collier AJ, Miranda OA, Dunn N, Chen D, Sabri S, Torre-Ubieta L, Clark AT, Plath K, Christofk HR, Kornblum HI, Gandal MJ, Novitch BG. Watanabe M, et al. Among authors: christofk hr. Stem Cell Reports. 2022 Oct 11;17(10):2220-2238. doi: 10.1016/j.stemcr.2022.08.013. Epub 2022 Sep 29. Stem Cell Reports. 2022. PMID: 36179695 Free PMC article.
ZFP36-mediated mRNA decay regulates metabolism.
Cicchetto AC, Jacobson EC, Sunshine H, Wilde BR, Krall AS, Jarrett KE, Sedgeman L, Turner M, Plath K, Iruela-Arispe ML, de Aguiar Vallim TQ, Christofk HR. Cicchetto AC, et al. Among authors: christofk hr. Cell Rep. 2023 May 30;42(5):112411. doi: 10.1016/j.celrep.2023.112411. Epub 2023 Apr 21. Cell Rep. 2023. PMID: 37086408 Free PMC article.
Metabolic Regulation of Tissue Stem Cells.
Shapira SN, Christofk HR. Shapira SN, et al. Among authors: christofk hr. Trends Cell Biol. 2020 Jul;30(7):566-576. doi: 10.1016/j.tcb.2020.04.004. Epub 2020 Apr 28. Trends Cell Biol. 2020. PMID: 32359707 Free PMC article. Review.
Challenges in Studying Stem Cell Metabolism.
Perez-Ramirez CA, Christofk HR. Perez-Ramirez CA, et al. Among authors: christofk hr. Cell Stem Cell. 2021 Mar 4;28(3):409-423. doi: 10.1016/j.stem.2021.02.016. Cell Stem Cell. 2021. PMID: 33667361 Free article. Review.
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