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Page 1
Optimising the yield from bronchoalveolar lavage on human participants in infectious disease immunology research.
Shaw JA, Meiring M, Allies D, Cruywagen L, Fisher TL, Kasavan K, Roos K, Botha SM, MacDonald C, Hiemstra AM, Simon D, van Rensburg I, Flinn M, Shabangu A, Kuivaniemi H, Tromp G, Malherbe ST, Walzl G, du Plessis N; Stellenbosch University Immunology Research Group Bronchoalveolar Lavage Study Consortium (SU IRG BAL Study Consortium). Shaw JA, et al. Among authors: hiemstra am. Sci Rep. 2023 May 31;13(1):8859. doi: 10.1038/s41598-023-35723-2. Sci Rep. 2023. PMID: 37258565 Free PMC article.
Prospective evaluation of host biomarkers other than interferon gamma in QuantiFERON Plus supernatants as candidates for the diagnosis of tuberculosis in symptomatic individuals.
Manngo PM, Gutschmidt A, Snyders CI, Mutavhatsindi H, Manyelo CM, Makhoba NS, Ahlers P, Hiemstra A, Stanley K, McAnda S, Kidd M, Malherbe ST, Walzl G, Chegou NN. Manngo PM, et al. J Infect. 2019 Sep;79(3):228-235. doi: 10.1016/j.jinf.2019.07.007. Epub 2019 Jul 15. J Infect. 2019. PMID: 31319143 Free PMC article.
RISK6, a 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response.
Penn-Nicholson A, Mbandi SK, Thompson E, Mendelsohn SC, Suliman S, Chegou NN, Malherbe ST, Darboe F, Erasmus M, Hanekom WA, Bilek N, Fisher M, Kaufmann SHE, Winter J, Murphy M, Wood R, Morrow C, Van Rhijn I, Moody B, Murray M, Andrade BB, Sterling TR, Sutherland J, Naidoo K, Padayatchi N, Walzl G, Hatherill M, Zak D, Scriba TJ; Adolescent Cohort Study team; GC6-74 Consortium; SATVI Clinical and Laboratory Team; ScreenTB Consortium; AE-TBC Consortium; RePORT Brazil Team; Peruvian Household Contacts Cohort Team; CAPRISA IMPRESS team. Penn-Nicholson A, et al. Sci Rep. 2020 May 25;10(1):8629. doi: 10.1038/s41598-020-65043-8. Sci Rep. 2020. PMID: 32451443 Free PMC article.
GPR183 Regulates Interferons, Autophagy, and Bacterial Growth During Mycobacterium tuberculosis Infection and Is Associated With TB Disease Severity.
Bartlett S, Gemiarto AT, Ngo MD, Sajiir H, Hailu S, Sinha R, Foo CX, Kleynhans L, Tshivhula H, Webber T, Bielefeldt-Ohmann H, West NP, Hiemstra AM, MacDonald CE, Christensen LVV, Schlesinger LS, Walzl G, Rosenkilde MM, Mandrup-Poulsen T, Ronacher K. Bartlett S, et al. Among authors: hiemstra am. Front Immunol. 2020 Nov 6;11:601534. doi: 10.3389/fimmu.2020.601534. eCollection 2020. Front Immunol. 2020. PMID: 33240287 Free PMC article.
Biomarker-guided tuberculosis preventive therapy (CORTIS): a randomised controlled trial.
Scriba TJ, Fiore-Gartland A, Penn-Nicholson A, Mulenga H, Kimbung Mbandi S, Borate B, Mendelsohn SC, Hadley K, Hikuam C, Kaskar M, Musvosvi M, Bilek N, Self S, Sumner T, White RG, Erasmus M, Jaxa L, Raphela R, Innes C, Brumskine W, Hiemstra A, Malherbe ST, Hassan-Moosa R, Tameris M, Walzl G, Naidoo K, Churchyard G, Hatherill M; CORTIS-01 Study Team. Scriba TJ, et al. Lancet Infect Dis. 2021 Mar;21(3):354-365. doi: 10.1016/S1473-3099(20)30914-2. Epub 2021 Jan 25. Lancet Infect Dis. 2021. PMID: 33508224 Free PMC article. Clinical Trial.
Higher SARS-CoV-2 seroprevalence in workers with lower socioeconomic status in Cape Town, South Africa.
Shaw JA, Meiring M, Cummins T, Chegou NN, Claassen C, Du Plessis N, Flinn M, Hiemstra A, Kleynhans L, Leukes V, Loxton AG, MacDonald C, Mtala N, Reuter H, Simon D, Stanley K, Tromp G, Preiser W, Malherbe ST, Walzl G. Shaw JA, et al. PLoS One. 2021 Feb 25;16(2):e0247852. doi: 10.1371/journal.pone.0247852. eCollection 2021. PLoS One. 2021. PMID: 33630977 Free PMC article.
Validation of a host blood transcriptomic biomarker for pulmonary tuberculosis in people living with HIV: a prospective diagnostic and prognostic accuracy study.
Mendelsohn SC, Fiore-Gartland A, Penn-Nicholson A, Mulenga H, Mbandi SK, Borate B, Hadley K, Hikuam C, Musvosvi M, Bilek N, Erasmus M, Jaxa L, Raphela R, Nombida O, Kaskar M, Sumner T, White RG, Innes C, Brumskine W, Hiemstra A, Malherbe ST, Hassan-Moosa R, Tameris M, Walzl G, Naidoo K, Churchyard G, Scriba TJ, Hatherill M; CORTIS-HR Study Team. Mendelsohn SC, et al. Lancet Glob Health. 2021 Jun;9(6):e841-e853. doi: 10.1016/S2214-109X(21)00045-0. Epub 2021 Apr 13. Lancet Glob Health. 2021. PMID: 33862012 Free PMC article.
Establishment of a Patient-Derived, Magnetic Levitation-Based, Three-Dimensional Spheroid Granuloma Model for Human Tuberculosis.
Kotze LA, Beltran CGG, Lang D, Loxton AG, Cooper S, Meiring M, Koegelenberg CFN, Allwood BW, Malherbe ST, Hiemstra AM, Glanzmann B, Kinnear C, Walzl G, du Plessis N. Kotze LA, et al. Among authors: hiemstra am. mSphere. 2021 Aug 25;6(4):e0055221. doi: 10.1128/mSphere.00552-21. Epub 2021 Jul 21. mSphere. 2021. PMID: 34287004 Free PMC article.
Longitudinal Dynamics of a Blood Transcriptomic Signature of Tuberculosis.
Mulenga H, Musvosvi M, Mendelsohn SC, Penn-Nicholson A, Kimbung Mbandi S, Fiore-Gartland A, Tameris M, Mabwe S, Africa H, Bilek N, Kafaar F, Khader SA, Carstens B, Hadley K, Hikuam C, Erasmus M, Jaxa L, Raphela R, Nombida O, Kaskar M, Nicol MP, Mbhele S, Van Heerden J, Innes C, Brumskine W, Hiemstra A, Malherbe ST, Hassan-Moosa R, Walzl G, Naidoo K, Churchyard G, Hatherill M, Scriba TJ; CORTIS Study Team. Mulenga H, et al. Am J Respir Crit Care Med. 2021 Dec 15;204(12):1463-1472. doi: 10.1164/rccm.202103-0548OC. Am J Respir Crit Care Med. 2021. PMID: 34520313 Free PMC article.
Diagnostic Accuracy of the Cepheid 3-gene Host Response Fingerstick Blood Test in a Prospective, Multi-site Study: Interim Results.
Sutherland JS, van der Spuy G, Gindeh A, Thuong NTT, Namuganga A, Owolabi O, Mayanja-Kizza H, Nsereko M, Thwaites G, Winter J, Dockrell HM, Scriba TJ, Geluk A, Corstjens P, Stanley K, Richardson T, Shaw JA, Smith B, Malherbe ST, Walzl G; TrENDx-TB Consortium. Sutherland JS, et al. Clin Infect Dis. 2022 Jul 6;74(12):2136-2141. doi: 10.1093/cid/ciab839. Clin Infect Dis. 2022. PMID: 34550342 Free PMC article.
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