Extrusion without a motor: a new take on the loop extrusion model of genome organization.
Brackley CA, Johnson J, Michieletto D, Morozov AN, Nicodemi M, Cook PR, Marenduzzo D.
Brackley CA, et al. Among authors: morozov an.
Nucleus. 2018 Jan 1;9(1):95-103. doi: 10.1080/19491034.2017.1421825.
Nucleus. 2018.
PMID: 29300120
Free PMC article.
However, the model requires a motor to generate the loops, and although cohesin is a strong candidate for the extruding factor, a suitable motor protein (or a motor activity in cohesin itself) has yet to be found. ...Our simulations uncover an interest …
However, the model requires a motor to generate the loops, and although cohesin is a strong candidate for the extruding factor …