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A non-clinical and clinical IUCLID database for 530 pharmaceuticals (part I): Methodological aspects of its development.
Regul Toxicol Pharmacol. 2023 Aug;142:105416. doi: 10.1016/j.yrtph.2023.105416. Epub 2023 May 28.
Regul Toxicol Pharmacol. 2023.
PMID: 37253405
Free article.
UDP-glucuronosyltransferases (UGTs) 2B7 and UGT2B17 display converse specificity in testosterone and epitestosterone glucuronidation, whereas UGT2A1 conjugates both androgens similarly.
Sten T, Bichlmaier I, Kuuranne T, Leinonen A, Yli-Kauhaluoma J, Finel M.
Sten T, et al. Among authors: bichlmaier i.
Drug Metab Dispos. 2009 Feb;37(2):417-23. doi: 10.1124/dmd.108.024844. Epub 2008 Nov 20.
Drug Metab Dispos. 2009.
PMID: 19022937
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Stereochemical and steric control of the UDP-glucuronosyltransferase-catalyzed conjugation reaction: a rational approach for the design of inhibitors for the human UGT2B7.
Bichlmaier I, Finel M, Sippl W, Yli-Kauhaluoma J.
Bichlmaier I, et al.
ChemMedChem. 2007 Dec;2(12):1730-40. doi: 10.1002/cmdc.200700122.
ChemMedChem. 2007.
PMID: 17943712
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Eudismic analysis of tricyclic sesquiterpenoid alcohols: lead structures for the design of potent inhibitors of the human UDP-glucuronosyltransferase 2B7.
Bichlmaier I, Kurkela M, Siiskonen A, Finel M, Yli-Kauhaluoma J.
Bichlmaier I, et al.
Bioorg Chem. 2007 Oct;35(5):386-400. doi: 10.1016/j.bioorg.2007.07.002. Epub 2007 Aug 15.
Bioorg Chem. 2007.
PMID: 17706742
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Potent inhibitors of the human UDP-glucuronosyltransferase 2B7 derived from the sesquiterpenoid alcohol longifolol.
Bichlmaier I, Kurkela M, Joshi T, Siiskonen A, Rüffer T, Lang H, Finel M, Yli-Kauhaluoma J.
Bichlmaier I, et al.
ChemMedChem. 2007 Jun;2(6):881-9. doi: 10.1002/cmdc.200600246.
ChemMedChem. 2007.
PMID: 17479992
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Isoform-selective inhibition of the human UDP-glucuronosyltransferase 2B7 by isolongifolol derivatives.
Bichlmaier I, Kurkela M, Joshi T, Siiskonen A, Rüffer T, Lang H, Suchanova B, Vahermo M, Finel M, Yli-Kauhaluoma J.
Bichlmaier I, et al.
J Med Chem. 2007 May 31;50(11):2655-64. doi: 10.1021/jm061204e. Epub 2007 May 3.
J Med Chem. 2007.
PMID: 17474732
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Chiral distinction between the enantiomers of bicyclic alcohols by UDP-glucuronosyltransferases 2B7 and 2B17.
Bichlmaier I, Siiskonen A, Kurkela M, Finel M, Yli-Kauhaluoma J.
Bichlmaier I, et al.
Biol Chem. 2006 Apr;387(4):407-16. doi: 10.1515/BC.2006.055.
Biol Chem. 2006.
PMID: 16606339
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Stereochemical sensitivity of the human UDP-glucuronosyltransferases 2B7 and 2B17.
Bichlmaier I, Siiskonen A, Finel M, Yli-Kauhaluoma J.
Bichlmaier I, et al.
J Med Chem. 2006 Mar 9;49(5):1818-27. doi: 10.1021/jm051142c.
J Med Chem. 2006.
PMID: 16509597
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