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Engineered bacteria to accelerate wound healing: an adaptive, randomised, double-blind, placebo-controlled, first-in-human phase 1 trial.
EClinicalMedicine. 2023 May 25;60:102014. doi: 10.1016/j.eclinm.2023.102014. eCollection 2023 Jun.
EClinicalMedicine. 2023.
PMID: 37251631
Free PMC article.
Accelerated wound healing in mice by on-site production and delivery of CXCL12 by transformed lactic acid bacteria.
Vågesjö E, Öhnstedt E, Mortier A, Lofton H, Huss F, Proost P, Roos S, Phillipson M.
Vågesjö E, et al. Among authors: ohnstedt e.
Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):1895-1900. doi: 10.1073/pnas.1716580115. Epub 2018 Feb 5.
Proc Natl Acad Sci U S A. 2018.
PMID: 29432190
Free PMC article.
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The discovery and development of topical medicines for wound healing.
Öhnstedt E, Lofton Tomenius H, Vågesjö E, Phillipson M.
Öhnstedt E, et al.
Expert Opin Drug Discov. 2019 May;14(5):485-497. doi: 10.1080/17460441.2019.1588879. Epub 2019 Mar 14.
Expert Opin Drug Discov. 2019.
PMID: 30870037
Review.
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Accelerated Wound Healing in Minipigs by On-Site Production and Delivery of CXCL12 by Transformed Lactic Acid Bacteria.
Öhnstedt E, Lofton Tomenius H, Frank P, Roos S, Vågesjö E, Phillipson M.
Öhnstedt E, et al.
Pharmaceutics. 2022 Jan 19;14(2):229. doi: 10.3390/pharmaceutics14020229.
Pharmaceutics. 2022.
PMID: 35213962
Free PMC article.
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Oral administration of CXCL12-expressing Limosilactobacillus reuteri improves colitis by local immunomodulatory actions in preclinical models.
Öhnstedt E, Doñas C, Parv K, Pang Y, Lofton Tomenius H, Carrasco López M, Gannavarapu VR, Choi J, Ovezik M, Frank P, Jorvid M, Roos S, Vågesjö E, Phillipson M.
Öhnstedt E, et al.
Am J Physiol Gastrointest Liver Physiol. 2024 May 23. doi: 10.1152/ajpgi.00022.2024. Online ahead of print.
Am J Physiol Gastrointest Liver Physiol. 2024.
PMID: 38780469
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