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APOL1 promotes endothelial cell activation beyond the glomerulus.
Carracedo M, Ericson E, Ågren R, Forslöw A, Madeyski-Bengtson K, Svensson A, Riddle R, Christoffersson J, González-King Garibotti H, Lazovic B, Hicks R, Buvall L, Fornoni A, Greasley PJ, Lal M. Carracedo M, et al. Among authors: hicks r. iScience. 2023 May 8;26(6):106830. doi: 10.1016/j.isci.2023.106830. eCollection 2023 Jun 16. iScience. 2023. PMID: 37250770 Free PMC article.
Decoding non-random mutational signatures at Cas9 targeted sites.
Taheri-Ghahfarokhi A, Taylor BJM, Nitsch R, Lundin A, Cavallo AL, Madeyski-Bengtson K, Karlsson F, Clausen M, Hicks R, Mayr LM, Bohlooly-Y M, Maresca M. Taheri-Ghahfarokhi A, et al. Among authors: hicks r. Nucleic Acids Res. 2018 Sep 19;46(16):8417-8434. doi: 10.1093/nar/gky653. Nucleic Acids Res. 2018. PMID: 30032200 Free PMC article.
A CRISP(e)R view on kidney organoids allows generation of an induced pluripotent stem cell-derived kidney model for drug discovery.
Boreström C, Jonebring A, Guo J, Palmgren H, Cederblad L, Forslöw A, Svensson A, Söderberg M, Reznichenko A, Nyström J, Patrakka J, Hicks R, Maresca M, Valastro B, Collén A. Boreström C, et al. Among authors: hicks r. Kidney Int. 2018 Dec;94(6):1099-1110. doi: 10.1016/j.kint.2018.05.003. Epub 2018 Jul 31. Kidney Int. 2018. PMID: 30072040 Free article.
In vivo genome and base editing of a human PCSK9 knock-in hypercholesterolemic mouse model.
Carreras A, Pane LS, Nitsch R, Madeyski-Bengtson K, Porritt M, Akcakaya P, Taheri-Ghahfarokhi A, Ericson E, Bjursell M, Perez-Alcazar M, Seeliger F, Althage M, Knöll R, Hicks R, Mayr LM, Perkins R, Lindén D, Borén J, Bohlooly-Y M, Maresca M. Carreras A, et al. Among authors: hicks r. BMC Biol. 2019 Jan 15;17(1):4. doi: 10.1186/s12915-018-0624-2. BMC Biol. 2019. PMID: 30646909 Free PMC article.
Rapid target validation in a Cas9-inducible hiPSC derived kidney model.
Shamshirgaran Y, Jonebring A, Svensson A, Leefa I, Bohlooly-Y M, Firth M, Woollard KJ, Hofherr A, Rogers IM, Hicks R. Shamshirgaran Y, et al. Among authors: hicks r. Sci Rep. 2021 Aug 16;11(1):16532. doi: 10.1038/s41598-021-95986-5. Sci Rep. 2021. PMID: 34400685 Free PMC article.
Human iPSC and CRISPR targeted gene knock-in strategy for studying the somatic TIE2L914F mutation in endothelial cells.
Lazovic B, Nguyen HT, Ansarizadeh M, Wigge L, Kohl F, Li S, Carracedo M, Kettunen J, Krimpenfort L, Elgendy R, Richter K, De Silva L, Bilican B, Singh P, Saxena P, Hong X, Eklund L, Hicks R. Lazovic B, et al. Among authors: hicks r. Angiogenesis. 2024 May 21. doi: 10.1007/s10456-024-09925-9. Online ahead of print. Angiogenesis. 2024. PMID: 38771392
1,716 results