In Silico Discovery and Predictive Modeling of Novel Acetylcholinesterase (AChE) Inhibitors for Alzheimer's Treatment.
Suha HN, Hossain MS, Rahman S, Alodhayb A, Hossain MM, Kawsar SMA, Poirier R, Uddin KM.
Suha HN, et al.
Med Chem. 2024 May 27. doi: 10.2174/0115734064304100240511112619. Online ahead of print.
Med Chem. 2024.
PMID: 38803179
By scrutinizing their interactions with 11 essential target proteins (AChE, Abeta, BChE, GSK-3beta, MAO B, PDE-9, Prion, PSEN-1, sEH, Tau, and TDP-43) and comparing them with established drugs such as donepezil, galantamine, memantine, and rivastigmine, ligand 14 em …
By scrutinizing their interactions with 11 essential target proteins (AChE, Abeta, BChE, GSK-3beta, MAO B, PDE-9, Prion, PSEN- …