Thelingwani RS - Search Results

1

Pharmacogenetics of pain management in Zimbabwean patients with sickle cell disease.

Mapira NL, Thelingwani RS, Chikwambi Z, Kuona P, Masimirembwa C. Mapira NL, et al. Among authors: thelingwani rs. Pharmacogenomics. 2023 May;24(7):359-369. doi: 10.2217/pgs-2023-0045. Epub 2023 May 30. Pharmacogenomics. 2023. PMID: 37248824 Free PMC article.

2

In vitro and in silico identification and characterization of thiabendazole as a mechanism-based inhibitor of CYP1A2 and simulation of possible pharmacokinetic drug-drug interactions.

Thelingwani RS, Zvada SP, Dolgos H, Ungell AL, Masimirembwa CM. Thelingwani RS, et al. Drug Metab Dispos. 2009 Jun;37(6):1286-94. doi: 10.1124/dmd.108.024604. Epub 2009 Mar 19. Drug Metab Dispos. 2009. PMID: 19299526

3

Potent inhibition of CYP1A2 by Frutinone A, an active ingredient of the broad spectrum antimicrobial herbal extract from P. fruticosa.

Thelingwani RS, Dhansay K, Smith P, Chibale K, Masimirembwa CM. Thelingwani RS, et al. Xenobiotica. 2012 Oct;42(10):989-1000. doi: 10.3109/00498254.2012.681077. Epub 2012 Apr 25. Xenobiotica. 2012. PMID: 22533317

4

Effect of NIPRISAN® on CYP3A4 activity in vitro.

Adzu B, Masimirembwa C, Mustapha KB, Thelingwani R, Kirim RA, Gamaniel KS. Adzu B, et al. Eur J Drug Metab Pharmacokinet. 2015 Mar;40(1):115-8. doi: 10.1007/s13318-014-0173-1. Epub 2014 Jan 24. Eur J Drug Metab Pharmacokinet. 2015. PMID: 24464299

5

The effect of the Pheroid delivery system on the in vitro metabolism and in vivo pharmacokinetics of artemisone.

Grobler L, Grobler A, Haynes R, Masimirembwa C, Thelingwani R, Steenkamp P, Steyn HS. Grobler L, et al. Expert Opin Drug Metab Toxicol. 2014 Mar;10(3):313-25. doi: 10.1517/17425255.2014.885503. Epub 2014 Feb 10. Expert Opin Drug Metab Toxicol. 2014. PMID: 24511903

6

Physicochemical and drug metabolism characterization of a series of 4-aminoquinoline-3-hydroxypyridin-4-one hybrid molecules with antimalarial activity.

Thelingwani R, Bonn B, Chibale K, Masimirembwa C. Thelingwani R, et al. Expert Opin Drug Metab Toxicol. 2014 Oct;10(10):1313-24. doi: 10.1517/17425255.2014.954547. Expert Opin Drug Metab Toxicol. 2014. PMID: 25219629

7

Evaluation of Herbal Medicines: Value Addition to Traditional Medicines Through Metabolism, Pharmacokinetic and Safety Studies.

Thelingwani R, Masimirembwa C. Thelingwani R, et al. Curr Drug Metab. 2014;15(10):942-52. doi: 10.2174/1389200216666150206125727. Curr Drug Metab. 2014. PMID: 25658125 Review.

8

Plasma Concentrations of Hepcidin in Anemic Zimbabwean Infants.

Mupfudze TG, Stoltzfus RJ, Rukobo S, Moulton LH, Humphrey JH, Prendergast AJ; SHINE Trial Team; Jones AD, Manges A, Mangwadu G, Maluccio JA, Mbuya MN, Ntozini R, Tielsch JM. Mupfudze TG, et al. PLoS One. 2015 Aug 7;10(8):e0135227. doi: 10.1371/journal.pone.0135227. eCollection 2015. PLoS One. 2015. PMID: 26252205 Free PMC article.

9

Characterisation of artemisinin-chloroquinoline hybrids for potential metabolic liabilities.

Thelingwani R, Leandersson C, Bonn B, Smith P, Chibale K, Masimirembwa C. Thelingwani R, et al. Xenobiotica. 2016;46(3):234-40. doi: 10.3109/00498254.2015.1070975. Epub 2015 Sep 4. Xenobiotica. 2016. PMID: 26338168

10

Community burden of undiagnosed HIV infection among adolescents in Zimbabwe following primary healthcare-based provider-initiated HIV testing and counselling: A cross-sectional survey.

Simms V, Dauya E, Dakshina S, Bandason T, McHugh G, Munyati S, Chonzi P, Kranzer K, Ncube G, Masimirembwa C, Thelingwani R, Apollo T, Hayes R, Weiss HA, Ferrand RA. Simms V, et al. PLoS Med. 2017 Jul 25;14(7):e1002360. doi: 10.1371/journal.pmed.1002360. eCollection 2017 Jul. PLoS Med. 2017. PMID: 28742829 Free PMC article.

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