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Immunoscore immune checkpoint using spatial quantitative analysis of CD8 and PD-L1 markers is predictive of the efficacy of anti- PD1/PD-L1 immunotherapy in non-small cell lung cancer.
Ghiringhelli F, Bibeau F, Greillier L, Fumet JD, Ilie A, Monville F, Laugé C, Catteau A, Boquet I, Majdi A, Morgand E, Oulkhouir Y, Brandone N, Adam J, Sbarrato T, Kassambara A, Fieschi J, Garcia S, Lepage AL, Tomasini P, Galon J. Ghiringhelli F, et al. Among authors: lepage al. EBioMedicine. 2023 Jun;92:104633. doi: 10.1016/j.ebiom.2023.104633. Epub 2023 May 25. EBioMedicine. 2023. PMID: 37244159 Free PMC article.
Multicenter Evaluation of a Novel ROS1 Immunohistochemistry Assay (SP384) for Detection of ROS1 Rearrangements in a Large Cohort of Lung Adenocarcinoma Patients.
Hofman V, Rouquette I, Long-Mira E, Piton N, Chamorey E, Heeke S, Vignaud JM, Yguel C, Mazières J, Lepage AL, Bibeau F, Begueret H, Lassalle S, Lalvée S, Zahaf K, Benzaquen J, Poudenx M, Marquette CH, Sabourin JC, Ilié M, Hofman P. Hofman V, et al. Among authors: lepage al. J Thorac Oncol. 2019 Jul;14(7):1204-1212. doi: 10.1016/j.jtho.2019.03.024. Epub 2019 Apr 15. J Thorac Oncol. 2019. PMID: 30999109 Free article.
Perineural Invasion in Human Cutaneous Squamous Cell Carcinoma Is Linked to Neurotrophins, Epithelial-Mesenchymal Transition, and NCAM1.
Brugière C, El Bouchtaoui M, Leboeuf C, Gapihan G, Ait El Far R, Sy M, Lepage AL, Ratajczak P, Janin A, Verneuil L. Brugière C, et al. Among authors: lepage al. J Invest Dermatol. 2018 Sep;138(9):2063-2066. doi: 10.1016/j.jid.2018.02.044. Epub 2018 Mar 28. J Invest Dermatol. 2018. PMID: 29601811 Free article. No abstract available.
ORGAVADS: establishment of tumor organoids from head and neck squamous cell carcinoma to assess their response to innovative therapies.
Perréard M, Florent R, Divoux J, Grellard JM, Lequesne J, Briand M, Clarisse B, Rousseau N, Lebreton E, Dubois B, Harter V, Lasne-Cardon A, Drouet J, Johnson A, Le Page AL, Bazille C, Jeanne C, Figeac M, Goardon N, Vaur D, Micault E, Humbert M, Thariat J, Babin E, Poulain L, Weiswald LB, Bastit V. Perréard M, et al. BMC Cancer. 2023 Mar 9;23(1):223. doi: 10.1186/s12885-023-10692-x. BMC Cancer. 2023. PMID: 36894916 Free PMC article.