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Preliminary In Vitro and In Vivo Insights of In Silico Candidate Repurposed Drugs for Alzheimer's Disease.
Life (Basel). 2023 Apr 27;13(5):1095. doi: 10.3390/life13051095.
Life (Basel). 2023.
PMID: 37240740
Free PMC article.
Pharmacological activation of the C5a receptor leads to stimulation of the β-adrenergic receptor and alleviates cognitive impairment in a murine model of familial Alzheimer's disease.
Fella E, Papacharalambous R, Kynigopoulos D, Ioannou M, Derua R, Christodoulou C, Stylianou M, Karaiskos C, Kagiava A, Petroula G, Pierides C, Kyriakou M, Koumas L, Costeas P, Panayiotou E.
Fella E, et al. Among authors: kynigopoulos d.
Front Immunol. 2022 Aug 26;13:947071. doi: 10.3389/fimmu.2022.947071. eCollection 2022.
Front Immunol. 2022.
PMID: 36091045
Free PMC article.
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Treatment of the CRND8 mouse model for cerebral amyloid angiopathy, exhibited increased levels of neuron specific enolase in brain tissue following long-term treatment with a modified C5a receptor agonist, accompanied by improved cognitive function.
Ioannou M, Fella E, Papacharalambous R, Kynigopoulos D, Panayiotou E.
Ioannou M, et al. Among authors: kynigopoulos d.
Biochem Biophys Res Commun. 2023 Oct 1;675:78-84. doi: 10.1016/j.bbrc.2023.07.001. Epub 2023 Jul 5.
Biochem Biophys Res Commun. 2023.
PMID: 37454400
Free article.
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Network Architecture Producing Swing to Stance Transitions in an Insect Walking System.
Strohmer B, Mantziaris C, Kynigopoulos D, Manoonpong P, Larsen LB, Büschges A.
Strohmer B, et al. Among authors: kynigopoulos d.
Front Insect Sci. 2022 Apr 15;2:818449. doi: 10.3389/finsc.2022.818449. eCollection 2022.
Front Insect Sci. 2022.
PMID: 38468811
Free PMC article.
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