Gkotsi DS - Search Results

1

Signaling Switching from Hedgehog-GLI to MAPK Signaling Potentially Serves as a Compensatory Mechanism in Melanoma Cell Lines Resistant to GANT-61.

Piteša N, Kurtović M, Bartoniček N, Gkotsi DS, Čonkaš J, Petrić T, Musani V, Ozretić P, Riobo-Del Galdo NA, Sabol M. Piteša N, et al. Among authors: gkotsi ds. Biomedicines. 2023 May 3;11(5):1353. doi: 10.3390/biomedicines11051353. Biomedicines. 2023. PMID: 37239024 Free PMC article.

2

Partial Truncation of the C-Terminal Domain of PTCH1 in Cancer Enhances Autophagy and Metabolic Adaptability.

Caballero-Ruiz B, Gkotsi DS, Ollerton H, Morales-Alcala CC, Bordone R, Jenkins GML, Di Magno L, Canettieri G, Riobo-Del Galdo NA. Caballero-Ruiz B, et al. Among authors: gkotsi ds. Cancers (Basel). 2023 Jan 6;15(2):369. doi: 10.3390/cancers15020369. Cancers (Basel). 2023. PMID: 36672319 Free PMC article.

3

PTCHD1 Binds Cholesterol but Not Sonic Hedgehog, Suggesting a Distinct Cellular Function.

Hiltunen MK, Timmis AJ, Thomsen M, Gkotsi DS, Iwaï H, Ribeiro OM, Goldman A, Riobo-Del Galdo NA. Hiltunen MK, et al. Among authors: gkotsi ds. Int J Mol Sci. 2023 Jan 31;24(3):2682. doi: 10.3390/ijms24032682. Int J Mol Sci. 2023. PMID: 36769003 Free PMC article.

4

Halogenases: a palette of emerging opportunities for synthetic biology-synthetic chemistry and C-H functionalisation.

Crowe C , Molyneux S , Sharma SV , Zhang Y , Gkotsi DS , Connaris H , Goss RJM . Crowe C , et al. Among authors: gkotsi ds. Chem Soc Rev. 2021 Sep 7;50(17):9443-9481. doi: 10.1039/d0cs01551b. Epub 2021 Aug 9. Chem Soc Rev. 2021. PMID: 34368824 Free PMC article. Review.

5

Nicotiana benthamiana as a Transient Expression Host to Produce Auxin Analogs.

Davis K, Gkotsi DS, Smith DRM, Goss RJM, Caputi L, O'Connor SE. Davis K, et al. Among authors: gkotsi ds. Front Plant Sci. 2020 Nov 20;11:581675. doi: 10.3389/fpls.2020.581675. eCollection 2020. Front Plant Sci. 2020. PMID: 33329644 Free PMC article.

6

Halogenases: structures and functions.

Ludewig H, Molyneux S, Ferrinho S, Guo K, Lynch R, Gkotsi DS, Goss RJ. Ludewig H, et al. Among authors: gkotsi ds. Curr Opin Struct Biol. 2020 Dec;65:51-60. doi: 10.1016/j.sbi.2020.05.012. Epub 2020 Jun 30. Curr Opin Struct Biol. 2020. PMID: 32619660 Review.

7

A marine viral halogenase that iodinates diverse substrates.

Gkotsi DS, Ludewig H, Sharma SV, Connolly JA, Dhaliwal J, Wang Y, Unsworth WP, Taylor RJK, McLachlan MMW, Shanahan S, Naismith JH, Goss RJM. Gkotsi DS, et al. Nat Chem. 2019 Dec;11(12):1091-1097. doi: 10.1038/s41557-019-0349-z. Epub 2019 Oct 14. Nat Chem. 2019. PMID: 31611633 Free PMC article.

8

Halogenases: powerful tools for biocatalysis (mechanisms applications and scope).

Gkotsi DS, Dhaliwal J, McLachlan MM, Mulholand KR, Goss RJ. Gkotsi DS, et al. Curr Opin Chem Biol. 2018 Apr;43:119-126. doi: 10.1016/j.cbpa.2018.01.002. Epub 2018 Feb 2. Curr Opin Chem Biol. 2018. PMID: 29414530 Review. No abstract available.

9

Promiscuous indolyl vinyl isonitrile synthases in the biogenesis and diversification of hapalindole-type alkaloids.

Ittiamornkul K, Zhu Q, Gkotsi DS, Smith DRM, Hillwig ML, Nightingale N, Goss RJM, Liu X. Ittiamornkul K, et al. Among authors: gkotsi ds. Chem Sci. 2015 Dec 1;6(12):6836-6840. doi: 10.1039/c5sc02919h. Epub 2015 Oct 6. Chem Sci. 2015. PMID: 29861925 Free PMC article.

10

The first one-pot synthesis of L-7-iodotryptophan from 7-iodoindole and serine, and an improved synthesis of other L-7-halotryptophans.

Smith DR, Willemse T, Gkotsi DS, Schepens W, Maes BU, Ballet S, Goss RJ. Smith DR, et al. Among authors: gkotsi ds. Org Lett. 2014 May 16;16(10):2622-5. doi: 10.1021/ol5007746. Epub 2014 May 7. Org Lett. 2014. PMID: 24805161

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