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Opposing effects of fructokinase C and A isoforms on fructose-induced metabolic syndrome in mice.
Ishimoto T, Lanaspa MA, Le MT, Garcia GE, Diggle CP, Maclean PS, Jackman MR, Asipu A, Roncal-Jimenez CA, Kosugi T, Rivard CJ, Maruyama S, Rodriguez-Iturbe B, Sánchez-Lozada LG, Bonthron DT, Sautin YY, Johnson RJ. Ishimoto T, et al. Among authors: garcia ge. Proc Natl Acad Sci U S A. 2012 Mar 13;109(11):4320-5. doi: 10.1073/pnas.1119908109. Epub 2012 Feb 27. Proc Natl Acad Sci U S A. 2012. PMID: 22371574 Free PMC article.
Obesity causes renal mitochondrial dysfunction and energy imbalance and accelerates chronic kidney disease in mice.
Andres-Hernando A, Lanaspa MA, Kuwabara M, Orlicky DJ, Cicerchi C, Bales E, Garcia GE, Roncal-Jimenez CA, Sato Y, Johnson RJ. Andres-Hernando A, et al. Among authors: garcia ge. Am J Physiol Renal Physiol. 2019 Oct 1;317(4):F941-F948. doi: 10.1152/ajprenal.00203.2019. Epub 2019 Aug 14. Am J Physiol Renal Physiol. 2019. PMID: 31411075 Free article.
Vasopressin mediates fructose-induced metabolic syndrome by activating the V1b receptor.
Andres-Hernando A, Jensen TJ, Kuwabara M, Orlicky DJ, Cicerchi C, Li N, Roncal-Jimenez CA, Garcia GE, Ishimoto T, Maclean PS, Bjornstad P, Sanchez-Lozada LG, Kanbay M, Nakagawa T, Johnson RJ, Lanaspa MA. Andres-Hernando A, et al. Among authors: garcia ge. JCI Insight. 2021 Jan 11;6(1):e140848. doi: 10.1172/jci.insight.140848. JCI Insight. 2021. PMID: 33320834 Free PMC article.
Uric acid stimulates fructokinase and accelerates fructose metabolism in the development of fatty liver.
Lanaspa MA, Sanchez-Lozada LG, Cicerchi C, Li N, Roncal-Jimenez CA, Ishimoto T, Le M, Garcia GE, Thomas JB, Rivard CJ, Andres-Hernando A, Hunter B, Schreiner G, Rodriguez-Iturbe B, Sautin YY, Johnson RJ. Lanaspa MA, et al. Among authors: garcia ge. PLoS One. 2012;7(10):e47948. doi: 10.1371/journal.pone.0047948. Epub 2012 Oct 24. PLoS One. 2012. PMID: 23112875 Free PMC article.
Endogenous fructose production and fructokinase activation mediate renal injury in diabetic nephropathy.
Lanaspa MA, Ishimoto T, Cicerchi C, Tamura Y, Roncal-Jimenez CA, Chen W, Tanabe K, Andres-Hernando A, Orlicky DJ, Finol E, Inaba S, Li N, Rivard CJ, Kosugi T, Sanchez-Lozada LG, Petrash JM, Sautin YY, Ejaz AA, Kitagawa W, Garcia GE, Bonthron DT, Asipu A, Diggle CP, Rodriguez-Iturbe B, Nakagawa T, Johnson RJ. Lanaspa MA, et al. Among authors: garcia ge. J Am Soc Nephrol. 2014 Nov;25(11):2526-38. doi: 10.1681/ASN.2013080901. Epub 2014 May 29. J Am Soc Nephrol. 2014. PMID: 24876114 Free PMC article.
Aging-associated renal disease in mice is fructokinase dependent.
Roncal-Jimenez CA, Ishimoto T, Lanaspa MA, Milagres T, Hernando AA, Jensen T, Miyazaki M, Doke T, Hayasaki T, Nakagawa T, Marumaya S, Long DA, Garcia GE, Kuwabara M, Sánchez-Lozada LG, Kang DH, Johnson RJ. Roncal-Jimenez CA, et al. Among authors: garcia ge. Am J Physiol Renal Physiol. 2016 Oct 1;311(4):F722-F730. doi: 10.1152/ajprenal.00306.2016. Epub 2016 Jul 27. Am J Physiol Renal Physiol. 2016. PMID: 27465991 Free PMC article.
Role of fructose and fructokinase in acute dehydration-induced vasopressin gene expression and secretion in mice.
Song 宋志林 Z, Roncal-Jimenez CA, Lanaspa-Garcia MA, Oppelt SA, Kuwabara M, Jensen T, Milagres T, Andres-Hernando A, Ishimoto T, Garcia GE, Johnson G, MacLean PS, Sanchez-Lozada LG, Tolan DR, Johnson RJ. Song 宋志林 Z, et al. Among authors: garcia ge. J Neurophysiol. 2017 Feb 1;117(2):646-654. doi: 10.1152/jn.00781.2016. Epub 2016 Nov 16. J Neurophysiol. 2017. PMID: 27852737 Free PMC article.
Effects of exogenous desmopressin on a model of heat stress nephropathy in mice.
Roncal-Jimenez CA, Milagres T, Andres-Hernando A, Kuwabara M, Jensen T, Song Z, Bjornstad P, Garcia GE, Sato Y, Sanchez-Lozada LG, Lanaspa MA, Johnson RJ. Roncal-Jimenez CA, et al. Among authors: garcia ge. Am J Physiol Renal Physiol. 2017 Mar 1;312(3):F418-F426. doi: 10.1152/ajprenal.00495.2016. Epub 2016 Dec 21. Am J Physiol Renal Physiol. 2017. PMID: 28003190 Free PMC article.
137 results