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Design and Optimization of Novel Benzimidazole- and Imidazo[4,5-b]pyridine-Based ATM Kinase Inhibitors with Subnanomolar Activities.
Dimitrov T, Moschopoulou AA, Seidel L, Kronenberger T, Kudolo M, Poso A, Geibel C, Wölffing P, Dauch D, Zender L, Schollmeyer D, Bajorath J, Forster M, Laufer S. Dimitrov T, et al. Among authors: zender l. J Med Chem. 2023 Jun 8;66(11):7304-7330. doi: 10.1021/acs.jmedchem.2c02104. Epub 2023 May 25. J Med Chem. 2023. PMID: 37226670
MYC determines lineage commitment in KRAS-driven primary liver cancer development.
D'Artista L, Moschopoulou AA, Barozzi I, Craig AJ, Seehawer M, Herrmann L, Minnich M, Kang TW, Rist E, Henning M, Klotz S, Heinzmann F, Harbig J, Sipos B, Longerich T, Eilers M, Dauch D, Zuber J, Wang XW, Zender L. D'Artista L, et al. Among authors: zender l. J Hepatol. 2023 Jul;79(1):141-149. doi: 10.1016/j.jhep.2023.02.039. Epub 2023 Mar 9. J Hepatol. 2023. PMID: 36906109 Free article.
First-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure.
Zwirner S, Abu Rmilah AA, Klotz S, Pfaffenroth B, Kloevekorn P, Moschopoulou AA, Schuette S, Haag M, Selig R, Li K, Zhou W, Nelson E, Poso A, Chen H, Amiot B, Jia Y, Minshew A, Michalak G, Cui W, Rist E, Longerich T, Jung B, Felgendreff P, Trompak O, Premsrirut PK, Gries K, Muerdter TE, Heinkele G, Wuestefeld T, Shapiro D, Weissbach M, Koenigsrainer A, Sipos B, Ab E, Zacarias MO, Theisgen S, Gruenheit N, Biskup S, Schwab M, Albrecht W, Laufer S, Nyberg S, Zender L. Zwirner S, et al. Among authors: zender l. Cell. 2024 Mar 28;187(7):1666-1684.e26. doi: 10.1016/j.cell.2024.02.023. Epub 2024 Mar 14. Cell. 2024. PMID: 38490194 Free PMC article. Clinical Trial.
Long-term prognostic factors for PRRT in neuroendocrine tumors.
Trautwein NF, Schwenck J, Jacoby J, Reischl G, Fiz F, Zender L, Dittmann H, Hinterleitner M, la Fougère C. Trautwein NF, et al. Among authors: zender l. Front Med (Lausanne). 2023 Jun 9;10:1169970. doi: 10.3389/fmed.2023.1169970. eCollection 2023. Front Med (Lausanne). 2023. PMID: 37359009 Free PMC article.
In vivo imaging of CD8+ T cells in metastatic cancer patients: first clinical experience with simultaneous [89Zr]Zr-Df-IAB22M2C PET/MRI.
Schwenck J, Sonanini D, Seyfried D, Ehrlichmann W, Kienzle G, Reischl G, Krezer P, Wilson I, Korn R, Gonzalez-Menendez I, Quintanilla-Martinez L, Seith F, Forschner A, Eigentler T, Zender L, Röcken M, Pichler BJ, Flatz L, Kneilling M, la Fougere C. Schwenck J, et al. Among authors: zender l. Theranostics. 2023 Apr 17;13(8):2408-2423. doi: 10.7150/thno.79976. eCollection 2023. Theranostics. 2023. PMID: 37215571 Free PMC article.
Advances in PET imaging of cancer.
Schwenck J, Sonanini D, Cotton JM, Rammensee HG, la Fougère C, Zender L, Pichler BJ. Schwenck J, et al. Among authors: zender l. Nat Rev Cancer. 2023 Jul;23(7):474-490. doi: 10.1038/s41568-023-00576-4. Epub 2023 May 31. Nat Rev Cancer. 2023. PMID: 37258875 Review.
NOTCH3 missense mutations as predictor of long-term response to gemcitabine in a patient with epithelioid hemangioendothelioma.
Schmidt M, Mattern S, Singer S, Schulze M, Biskup S, Krumm P, Lauer UM, Zender L, Hinterleitner C, Hinterleitner M. Schmidt M, et al. Among authors: zender l. J Cancer Res Clin Oncol. 2023 Aug;149(9):6753-6757. doi: 10.1007/s00432-023-04598-1. Epub 2023 Feb 7. J Cancer Res Clin Oncol. 2023. PMID: 36749424 Free PMC article. Review.
184 results