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First-in-human, double-blind, randomized phase 1b study of peptide immunotherapy IMCY-0098 in new-onset type 1 diabetes.
BMC Med. 2023 May 24;21(1):190. doi: 10.1186/s12916-023-02900-z.
BMC Med. 2023.
PMID: 37226224
Free PMC article.
Clinical Trial.
Retroviral vectors induce epigenetic chromatin modifications and IL-10 production in transduced B cells via activation of toll-like receptor 2.
Ahangarani RR, Janssens W, Carlier V, Vanderelst L, Vandendriessche T, Chuah M, Jacquemin M, Saint-Remy JM.
Ahangarani RR, et al.
Mol Ther. 2011 Apr;19(4):711-22. doi: 10.1038/mt.2010.275. Epub 2010 Dec 14.
Mol Ther. 2011.
PMID: 21157434
Free PMC article.
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In vivo induction of type 1-like regulatory T cells using genetically modified B cells confers long-term IL-10-dependent antigen-specific unresponsiveness.
Ahangarani RR, Janssens W, VanderElst L, Carlier V, VandenDriessche T, Chuah M, Weynand B, Vanoirbeek JA, Jacquemin M, Saint-Remy JM.
Ahangarani RR, et al.
J Immunol. 2009 Dec 15;183(12):8232-43. doi: 10.4049/jimmunol.0901777.
J Immunol. 2009.
PMID: 20007587
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