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Supraphysiological FOXP3 expression in human CAR-Tregs results in improved stability, efficacy, and safety of CAR-Treg products for clinical application.
Henschel P, Landwehr-Kenzel S, Engels N, Schienke A, Kremer J, Riet T, Redel N, Iordanidis K, Saetzler V, John K, Heider M, Hardtke-Wolenski M, Wedemeyer H, Jaeckel E, Noyan F. Henschel P, et al. Among authors: landwehr kenzel s. J Autoimmun. 2023 Jul;138:103057. doi: 10.1016/j.jaut.2023.103057. Epub 2023 May 23. J Autoimmun. 2023. PMID: 37224732 Free article.
Adoptive transfer of ex vivo expanded regulatory T cells improves immune cell engraftment and therapy-refractory chronic GvHD.
Landwehr-Kenzel S, Müller-Jensen L, Kuehl JS, Abou-El-Enein M, Hoffmann H, Muench S, Kaiser D, Roemhild A, von Bernuth H, Voeller M, Schmueck-Henneresse M, Gruhn B, Stervbo U, Babel N, Volk HD, Reinke P. Landwehr-Kenzel S, et al. Mol Ther. 2022 Jun 1;30(6):2298-2314. doi: 10.1016/j.ymthe.2022.02.025. Epub 2022 Feb 28. Mol Ther. 2022. PMID: 35240319 Free PMC article.
Initial presenting manifestations in 16,486 patients with inborn errors of immunity include infections and noninfectious manifestations.
Thalhammer J, Kindle G, Nieters A, Rusch S, Seppänen MRJ, Fischer A, Grimbacher B, Edgar D, Buckland M, Mahlaoui N, Ehl S; European Society for Immunodeficiencies Registry Working Party. Thalhammer J, et al. J Allergy Clin Immunol. 2021 Nov;148(5):1332-1341.e5. doi: 10.1016/j.jaci.2021.04.015. Epub 2021 Apr 23. J Allergy Clin Immunol. 2021. PMID: 33895260 Free article.
Regulatory T cells for minimising immune suppression in kidney transplantation: phase I/IIa clinical trial.
Roemhild A, Otto NM, Moll G, Abou-El-Enein M, Kaiser D, Bold G, Schachtner T, Choi M, Oellinger R, Landwehr-Kenzel S, Juerchott K, Sawitzki B, Giesler C, Sefrin A, Beier C, Wagner DL, Schlickeiser S, Streitz M, Schmueck-Henneresse M, Amini L, Stervbo U, Babel N, Volk HD, Reinke P. Roemhild A, et al. Among authors: landwehr kenzel s. BMJ. 2020 Oct 21;371:m3734. doi: 10.1136/bmj.m3734. BMJ. 2020. PMID: 33087345 Free PMC article. Clinical Trial.
Comprehensive Characterization of a Next-Generation Antiviral T-Cell Product and Feasibility for Application in Immunosuppressed Transplant Patients.
Amini L, Vollmer T, Wendering DJ, Jurisch A, Landwehr-Kenzel S, Otto NM, Jürchott K, Volk HD, Reinke P, Schmueck-Henneresse M. Amini L, et al. Among authors: landwehr kenzel s. Front Immunol. 2019 May 28;10:1148. doi: 10.3389/fimmu.2019.01148. eCollection 2019. Front Immunol. 2019. PMID: 31191530 Free PMC article.
Human CD45RA(-) FoxP3(hi) Memory-Type Regulatory T Cells Show Distinct TCR Repertoires With Conventional T Cells and Play an Important Role in Controlling Early Immune Activation.
Lei H, Kuchenbecker L, Streitz M, Sawitzki B, Vogt K, Landwehr-Kenzel S, Millward J, Juelke K, Babel N, Neumann A, Reinke P, Volk HD. Lei H, et al. Among authors: landwehr kenzel s. Am J Transplant. 2015 Oct;15(10):2625-35. doi: 10.1111/ajt.13315. Epub 2015 May 18. Am J Transplant. 2015. PMID: 25988290 Free article.
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