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Molecular basis of differential HLA class I-restricted T cell recognition of a highly networked HIV peptide.
Li X, Singh NK, Collins DR, Ng R, Zhang A, Lamothe-Molina PA, Shahinian P, Xu S, Tan K, Piechocka-Trocha A, Urbach JM, Weber JK, Gaiha GD, Takou Mbah OC, Huynh T, Cheever S, Chen J, Birnbaum M, Zhou R, Walker BD, Wang JH. Li X, et al. Among authors: singh nk. Nat Commun. 2023 May 22;14(1):2929. doi: 10.1038/s41467-023-38573-8. Nat Commun. 2023. PMID: 37217466 Free PMC article.
HLA class-I-peptide stability mediates CD8+ T cell immunodominance hierarchies and facilitates HLA-associated immune control of HIV.
Kaseke C, Park RJ, Singh NK, Koundakjian D, Bashirova A, Garcia Beltran WF, Takou Mbah OC, Ma J, Senjobe F, Urbach JM, Nathan A, Rossin EJ, Tano-Menka R, Khatri A, Piechocka-Trocha A, Waring MT, Birnbaum ME, Baker BM, Carrington M, Walker BD, Gaiha GD. Kaseke C, et al. Among authors: singh nk. Cell Rep. 2021 Jul 13;36(2):109378. doi: 10.1016/j.celrep.2021.109378. Cell Rep. 2021. PMID: 34260940 Free PMC article.
Structure-guided T cell vaccine design for SARS-CoV-2 variants and sarbecoviruses.
Nathan A, Rossin EJ, Kaseke C, Park RJ, Khatri A, Koundakjian D, Urbach JM, Singh NK, Bashirova A, Tano-Menka R, Senjobe F, Waring MT, Piechocka-Trocha A, Garcia-Beltran WF, Iafrate AJ, Naranbhai V, Carrington M, Walker BD, Gaiha GD. Nathan A, et al. Among authors: singh nk. Cell. 2021 Aug 19;184(17):4401-4413.e10. doi: 10.1016/j.cell.2021.06.029. Epub 2021 Jun 30. Cell. 2021. PMID: 34265281 Free PMC article.
Identification of Highly Cross-Reactive Mimotopes for a Public T Cell Response in Murine Melanoma.
Grace BE, Backlund CM, Morgan DM, Kang BH, Singh NK, Huisman BD, Rappazzo CG, Moynihan KD, Maiorino L, Dobson CS, Kyung T, Gordon KS, Holec PV, Mbah OCT, Garafola D, Wu S, Love JC, Wittrup KD, Irvine DJ, Birnbaum ME. Grace BE, et al. Among authors: singh nk. Front Immunol. 2022 Jun 23;13:886683. doi: 10.3389/fimmu.2022.886683. eCollection 2022. Front Immunol. 2022. PMID: 35812387 Free PMC article.
Polymorphic residues in HLA-B that mediate HIV control distinctly modulate peptide interactions with both TCR and KIR molecules.
Tano-Menka R, Singh NK, Muzhingi I, Li X, Mandanas MV, Kaseke C, Crain CR, Zhang A, Ogunshola FJ, Vecchiarello L, Piechocka-Trocha A, Bashirova A, Birnbaum ME, Carrington M, Walker BD, Gaiha GD. Tano-Menka R, et al. Among authors: singh nk. Structure. 2024 May 7:S0969-2126(24)00141-2. doi: 10.1016/j.str.2024.04.015. Online ahead of print. Structure. 2024. PMID: 38733995 Free article.
How an alloreactive T-cell receptor achieves peptide and MHC specificity.
Wang Y, Singh NK, Spear TT, Hellman LM, Piepenbrink KH, McMahan RH, Rosen HR, Vander Kooi CW, Nishimura MI, Baker BM. Wang Y, et al. Among authors: singh nk. Proc Natl Acad Sci U S A. 2017 Jun 13;114(24):E4792-E4801. doi: 10.1073/pnas.1700459114. Epub 2017 Jun 1. Proc Natl Acad Sci U S A. 2017. PMID: 28572406 Free PMC article.
1,164 results