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Evolution-guided engineering of trans-acyltransferase polyketide synthases.
Mabesoone MFJ, Leopold-Messer S, Minas HA, Chepkirui C, Chawengrum P, Reiter S, Meoded RA, Wolf S, Genz F, Magnus N, Piechulla B, Walker AS, Piel J. Mabesoone MFJ, et al. Among authors: meoded ra. Science. 2024 Mar 22;383(6689):1312-1317. doi: 10.1126/science.adj7621. Epub 2024 Mar 21. Science. 2024. PMID: 38513027
Modular Oxime Formation by a trans-AT Polyketide Synthase.
Minas HA, François RMM, Hemmerling F, Fraley AE, Dieterich CL, Rüdisser SH, Meoded RA, Collin S, Weissman KJ, Gruez A, Piel J. Minas HA, et al. Among authors: meoded ra. Angew Chem Int Ed Engl. 2023 Aug 21;62(34):e202304481. doi: 10.1002/anie.202304481. Epub 2023 Jul 11. Angew Chem Int Ed Engl. 2023. PMID: 37216334
Automated structure prediction of trans-acyltransferase polyketide synthase products.
Helfrich EJN, Ueoka R, Dolev A, Rust M, Meoded RA, Bhushan A, Califano G, Costa R, Gugger M, Steinbeck C, Moreno P, Piel J. Helfrich EJN, et al. Among authors: meoded ra. Nat Chem Biol. 2019 Aug;15(8):813-821. doi: 10.1038/s41589-019-0313-7. Epub 2019 Jul 15. Nat Chem Biol. 2019. PMID: 31308532 Free PMC article.
In plaque-mass spectrometry imaging of a bloom-forming alga during viral infection reveals a metabolic shift towards odd-chain fatty acid lipids.
Schleyer G, Shahaf N, Ziv C, Dong Y, Meoded RA, Helfrich EJN, Schatz D, Rosenwasser S, Rogachev I, Aharoni A, Piel J, Vardi A. Schleyer G, et al. Among authors: meoded ra. Nat Microbiol. 2019 Mar;4(3):527-538. doi: 10.1038/s41564-018-0336-y. Epub 2019 Feb 4. Nat Microbiol. 2019. PMID: 30718847 Free PMC article.
14 results