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Predictive scaling of fiber-based protein A capture chromatography using mechanistic modeling.
Biotechnol Bioeng. 2023 May 20. doi: 10.1002/bit.28434. Online ahead of print.
Biotechnol Bioeng. 2023.
PMID: 37209384
Multiproduct Resin Reuse for Clinical and Commercial Manufacturing-Methodology and Acceptance Criteria.
Sharnez R, Doares S, Manning S, Mehta K, Mahajan E, To A, Daniels W, Glynn J, Dhamane S, Wen X, Wang Y, Gour P, Guenther C, Foley D, Hayes R, Mott A, Prabhu S, Tavalsky D, Hendershot M, Haas D, Hesslein A, Schuelke N, Tjandra H.
Sharnez R, et al. Among authors: hesslein a.
PDA J Pharm Sci Technol. 2018 Nov-Dec;72(6):584-598. doi: 10.5731/pdajpst.2016.007245. Epub 2018 Jul 20.
PDA J Pharm Sci Technol. 2018.
PMID: 30030349
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BAY 81-8973, a full-length recombinant factor VIII: manufacturing processes and product characteristics.
Garger S, Severs J, Regan L, Hesslein A, Ignowski J, Wu P, Long E, Gupta S, Liu S, Wang W.
Garger S, et al. Among authors: hesslein a.
Haemophilia. 2017 Mar;23(2):e67-e78. doi: 10.1111/hae.13148. Epub 2016 Dec 19.
Haemophilia. 2017.
PMID: 27995680
Review.
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Targeted inhibition of activated protein C by a non-active-site inhibitory antibody to treat hemophilia.
Zhao XY, Wilmen A, Wang D, Wang X, Bauzon M, Kim JY, Linden L, Li L, Egner U, Marquardt T, Moosmayer D, Tebbe J, Glück JM, Ellinger P, McLean K, Yuan S, Yegneswaran S, Jiang X, Evans V, Gu JM, Schneider D, Zhu Y, Xu Y, Mallari C, Hesslein A, Wang Y, Schmidt N, Gutberlet K, Ruehl-Fehlert C, Freyberger A, Hermiston T, Patel C, Sim D, Mosnier LO, Laux V.
Zhao XY, et al. Among authors: hesslein a.
Nat Commun. 2020 Jun 12;11(1):2992. doi: 10.1038/s41467-020-16720-9.
Nat Commun. 2020.
PMID: 32532974
Free PMC article.
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Exploration of the conserved A+C wobble pair within the ribosomal peptidyl transferase center using affinity purified mutant ribosomes.
Hesslein AE, Katunin VI, Beringer M, Kosek AB, Rodnina MV, Strobel SA.
Hesslein AE, et al.
Nucleic Acids Res. 2004 Jul 15;32(12):3760-70. doi: 10.1093/nar/gkh672. Print 2004.
Nucleic Acids Res. 2004.
PMID: 15256541
Free PMC article.
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Preparation and reactivity studies of synthetic microperoxidases containing b-type heme.
Ryabova ES, Dikiy A, Hesslein AE, Bjerrum MJ, Ciurli S, Nordlander E.
Ryabova ES, et al. Among authors: hesslein ae.
J Biol Inorg Chem. 2004 Jun;9(4):385-95. doi: 10.1007/s00775-004-0532-5. Epub 2004 Mar 24.
J Biol Inorg Chem. 2004.
PMID: 15042435
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