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Overexpression of VIRMA confers vulnerability to breast cancers via the m6A-dependent regulation of unfolded protein response.
Lee Q, Song R, Phan DAV, Pinello N, Tieng J, Su A, Halstead JM, Wong ACH, van Geldermalsen M, Lee BS, Rong B, Cook KM, Larance M, Liu R, Lan F, Tiffen JC, Wong JJ. Lee Q, et al. Among authors: van geldermalsen m. Cell Mol Life Sci. 2023 May 19;80(6):157. doi: 10.1007/s00018-023-04799-4. Cell Mol Life Sci. 2023. PMID: 37208522 Free PMC article.
Targeting glutamine transport to suppress melanoma cell growth.
Wang Q, Beaumont KA, Otte NJ, Font J, Bailey CG, van Geldermalsen M, Sharp DM, Tiffen JC, Ryan RM, Jormakka M, Haass NK, Rasko JE, Holst J. Wang Q, et al. Among authors: van geldermalsen m. Int J Cancer. 2014 Sep 1;135(5):1060-71. doi: 10.1002/ijc.28749. Epub 2014 Feb 17. Int J Cancer. 2014. PMID: 24531984 Free article.
Targeting ASCT2-mediated glutamine uptake blocks prostate cancer growth and tumour development.
Wang Q, Hardie RA, Hoy AJ, van Geldermalsen M, Gao D, Fazli L, Sadowski MC, Balaban S, Schreuder M, Nagarajah R, Wong JJ, Metierre C, Pinello N, Otte NJ, Lehman ML, Gleave M, Nelson CC, Bailey CG, Ritchie W, Rasko JE, Holst J. Wang Q, et al. Among authors: van geldermalsen m. J Pathol. 2015 Jul;236(3):278-89. doi: 10.1002/path.4518. Epub 2015 Apr 7. J Pathol. 2015. PMID: 25693838 Free PMC article.
Correction: Overexpression of VIRMA confers vulnerability to breast cancers via the m6A-dependent regulation of unfolded protein response.
Lee Q, Song R, Phan DAV, Pinello N, Tieng J, Su A, Halstead JM, Wong ACH, van Geldermalsen M, Lee BS, Rong B, Cook KM, Larance M, Liu R, Lan F, Tiffen JC, Wong JJ. Lee Q, et al. Among authors: van geldermalsen m. Cell Mol Life Sci. 2023 Jul 14;80(8):204. doi: 10.1007/s00018-023-04825-5. Cell Mol Life Sci. 2023. PMID: 37450040 Free PMC article. No abstract available.
Glutamine addiction promotes glucose oxidation in triple-negative breast cancer.
Quek LE, van Geldermalsen M, Guan YF, Wahi K, Mayoh C, Balaban S, Pang A, Wang Q, Cowley MJ, Brown KK, Turner N, Hoy AJ, Holst J. Quek LE, et al. Among authors: van geldermalsen m. Oncogene. 2022 Aug;41(34):4066-4078. doi: 10.1038/s41388-022-02408-5. Epub 2022 Jul 18. Oncogene. 2022. PMID: 35851845 Free PMC article.
LAT1 is a putative therapeutic target in endometrioid endometrial carcinoma.
Marshall AD, van Geldermalsen M, Otte NJ, Anderson LA, Lum T, Vellozzi MA, Zhang BK, Thoeng A, Wang Q, Rasko JE, Holst J. Marshall AD, et al. Among authors: van geldermalsen m. Int J Cancer. 2016 Dec 1;139(11):2529-39. doi: 10.1002/ijc.30371. Epub 2016 Aug 16. Int J Cancer. 2016. PMID: 27486861 Free article.
RAB27A promotes melanoma cell invasion and metastasis via regulation of pro-invasive exosomes.
Guo D, Lui GYL, Lai SL, Wilmott JS, Tikoo S, Jackett LA, Quek C, Brown DL, Sharp DM, Kwan RYQ, Chacon D, Wong JH, Beck D, van Geldermalsen M, Holst J, Thompson JF, Mann GJ, Scolyer RA, Stow JL, Weninger W, Haass NK, Beaumont KA. Guo D, et al. Among authors: van geldermalsen m. Int J Cancer. 2019 Jun 15;144(12):3070-3085. doi: 10.1002/ijc.32064. Epub 2019 Jan 3. Int J Cancer. 2019. PMID: 30556600 Free article.
15 results